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Conservation and Variability of Synaptonemal Complex Proteins in Phylogenesis of Eukaryotes
Joint Authors
Bogdanov, Yuri F.
Grishaeva, Tatiana M.
Source
International Journal of Evolutionary Biology
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-23
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
The problems of the origin and evolution of meiosis include the enigmatic variability of the synaptonemal complexes (SCs) which, being morphology similar, consist of different proteins in different eukaryotic phyla.
Using bioinformatics methods, we monitored all available eukaryotic proteomes to find proteins similar to known SC proteins of model organisms.
We found proteins similar to SC lateral element (LE) proteins and possessing the HORMA domain in the majority of the eukaryotic taxa and assume them the most ancient among all SC proteins.
Vertebrate LE proteins SYCP2, SYCP3, and SC65 proved to have related proteins in many invertebrate taxa.
Proteins of SC central space are most evolutionarily variable.
It means that different protein-protein interactions can exist to connect LEs.
Proteins similar to the known SC proteins were not found in Euglenophyta, Chrysophyta, Charophyta, Xanthophyta, Dinoflagellata, and primitive Coelomata.
We conclude that different proteins whose common feature is the presence of domains with a certain conformation are involved in the formation of the SC in different eukaryotic phyla.
This permits a targeted search for orthologs of the SC proteins using phylogenetic trees.
Here we consider example of phylogenetic trees for protozoans, fungi, algae, mosses, and flowering plants.
American Psychological Association (APA)
Grishaeva, Tatiana M.& Bogdanov, Yuri F.. 2014. Conservation and Variability of Synaptonemal Complex Proteins in Phylogenesis of Eukaryotes. International Journal of Evolutionary Biology،Vol. 2014, no. 2014, pp.1-16.
https://search.emarefa.net/detail/BIM-503715
Modern Language Association (MLA)
Grishaeva, Tatiana M.& Bogdanov, Yuri F.. Conservation and Variability of Synaptonemal Complex Proteins in Phylogenesis of Eukaryotes. International Journal of Evolutionary Biology No. 2014 (2014), pp.1-16.
https://search.emarefa.net/detail/BIM-503715
American Medical Association (AMA)
Grishaeva, Tatiana M.& Bogdanov, Yuri F.. Conservation and Variability of Synaptonemal Complex Proteins in Phylogenesis of Eukaryotes. International Journal of Evolutionary Biology. 2014. Vol. 2014, no. 2014, pp.1-16.
https://search.emarefa.net/detail/BIM-503715
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-503715