Current Status of New Anticoagulants in the Management of Venous Thromboembolism
Joint Authors
Montoya, Roberto C.
Gajra, Ajeet
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-08
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Venous Thromboembolism, manifested as deep venous thrombosis and pulmonary embolism, is a common problem associated with significant morbidity, mortality, and resource expenditure.
Unfractionated heparin, low-molecular-weight heparin, and vitamin K antagonists are the most common treatment and prophylaxis, and have demonstrated their efficacy in a vast number of previous studies.
Despite their broad use, these agents have important limitations that have led to the development of new drugs in a bid to overcome the disadvantages of the old ones without decreasing their therapeutic effect.
These novel medications, some approved and others in different stages of development, include direct thrombin inhibitors like dabigatran etexilate, and direct activated factor X inhibitors like rivaroxaban.
The current paper will review the characteristics, clinical trial results, and current and potential therapeutic uses of these new agents with a focus on the categories of direct thrombin inhibitors and activated factor X inhibitors.
American Psychological Association (APA)
Montoya, Roberto C.& Gajra, Ajeet. 2012. Current Status of New Anticoagulants in the Management of Venous Thromboembolism. Advances in Hematology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-503725
Modern Language Association (MLA)
Montoya, Roberto C.& Gajra, Ajeet. Current Status of New Anticoagulants in the Management of Venous Thromboembolism. Advances in Hematology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-503725
American Medical Association (AMA)
Montoya, Roberto C.& Gajra, Ajeet. Current Status of New Anticoagulants in the Management of Venous Thromboembolism. Advances in Hematology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-503725
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-503725