Neurodegeneration with Brain Iron Accumulation in an Eleven-Year-Old Jamaican Male

Abstract EN

We present a case of an eleven-year-old boy presenting with progressive extrapyramidal signs and dementia.

His imaging findings demonstrated the classic eye-of-the-tiger sign on T2W magnetic resonance imaging.

He was diagnosed with pantothenate kinase-associated neurodegeneration (PKAN).

This is a rare autosomal recessive inborn error of coenzyme A metabolism, caused by mutations in PANK2.

This is the first reported case of PKAN from the Caribbean.