![](/images/graphics-bg.png)
Optimization and Validation of RP-HPLC-UVVis Method for Determination Phenolic Compounds in Several Personal Care Products
Joint Authors
Assim, Zaini Bin
Ahmad, Fasihuddin Badruddin
Akkbik, Mohammed
Source
International Journal of Analytical Chemistry
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-23
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
An HPLC method with ultraviolet-visible spectrophotometry detection has been optimized and validated for the simultaneous determination of phenolic compounds, such as butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) as antioxidants, and octyl methyl cinnamate (OMC) as UVB-filter in several personal care products.
The dynamic range was between 1 to 250 mg/L with relative standard deviation less than 0.25% (n=4).
Limits of detection for BHA, BHT, and OMC were 0.196, 0.170, and 0.478 mg/L, respectively.
While limits of quantification for BHA, BHT, and OMC were 0.593, 0.515, and 1.448 mg/L, respectively.
The recovery for BHA, BHT, and OMC was ranged from 92.1–105.9%, 83.2–108.9%, and 87.3–103.7%, respectively.
The concentration ranges of BHA, BHT, and OMC in 12 commercial personal care samples were 0.13–4.85, 0.16–2.30, and 0.12–65.5 mg/g, respectively.
The concentrations of phenolic compounds in these personal care samples were below than maximum allowable concentration in personal care formulation, that is, 0.0004–10 mg/g, 0.002–5 mg/g, and up to 100 mg/g for BHA, BHT, and OMC, respectively.
American Psychological Association (APA)
Akkbik, Mohammed& Assim, Zaini Bin& Ahmad, Fasihuddin Badruddin. 2011. Optimization and Validation of RP-HPLC-UVVis Method for Determination Phenolic Compounds in Several Personal Care Products. International Journal of Analytical Chemistry،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-503892
Modern Language Association (MLA)
Akkbik, Mohammed…[et al.]. Optimization and Validation of RP-HPLC-UVVis Method for Determination Phenolic Compounds in Several Personal Care Products. International Journal of Analytical Chemistry No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-503892
American Medical Association (AMA)
Akkbik, Mohammed& Assim, Zaini Bin& Ahmad, Fasihuddin Badruddin. Optimization and Validation of RP-HPLC-UVVis Method for Determination Phenolic Compounds in Several Personal Care Products. International Journal of Analytical Chemistry. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-503892
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-503892