Lipid Mediators in Acne
Joint Authors
Camera, Emanuela
Ottaviani, Monica
Picardo, Mauro
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-08-25
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Multiple factors are involved in acne pathogenesis, and sebum secretion is one of the main ones.
The role sebum plays in acne development has not been completely elucidated yet; however, increasing amounts of data seem to confirm the presence of alterations in sebum from acne patients.
Altered ratio between saturated and unsaturated fatty acids has been indicated as an important feature to be considered in addition to the altered amount of specific fatty acids such as linoleic acid.
Furthermore, particular attention has been focused on squalene peroxide that seems to be able to induce an inflammatory response beyond cytotoxicity and comedones formation.
Moreover, recent data suggest that lipid mediators are able to interfere with sebocytes differentiation and sebogenesis through the activation of pathways related to peroxisome proliferators-activated receptors.
Understanding the factors and mechanisms that regulate sebum production is needed in order to identify novel therapeutic strategies for acne treatment.
American Psychological Association (APA)
Ottaviani, Monica& Camera, Emanuela& Picardo, Mauro. 2010. Lipid Mediators in Acne. Mediators of Inflammation،Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-503894
Modern Language Association (MLA)
Ottaviani, Monica…[et al.]. Lipid Mediators in Acne. Mediators of Inflammation No. 2010 (2010), pp.1-6.
https://search.emarefa.net/detail/BIM-503894
American Medical Association (AMA)
Ottaviani, Monica& Camera, Emanuela& Picardo, Mauro. Lipid Mediators in Acne. Mediators of Inflammation. 2010. Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-503894
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-503894