NLRP3 Inflammasome and MSEAE
Joint Authors
Inoue, Makoto
Shinohara, Mari L.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-01-08
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Inflammasomes are cytosolic sensors that detect pathogens and danger signals in the innate immune system.
The NLRP3 inflammasome is currently the most fully characterized inflammasome and is known to detect a wide array of microbes and endogenous damage-associated molecules.
Possible involvement of the NLRP3 inflammasome (or inflammasomes) in the development of multiple sclerosis (MS) was suggested in a number of studies.
Recent studies showed that the NLRP3 inflammasome exacerbates experimental autoimmune encephalomyelitis (EAE), an animal model of MS, although EAE can also develop without the NLRP3 inflammasome.
In this paper, we discuss the NLRP3 inflammasome in MS and EAE development.
American Psychological Association (APA)
Inoue, Makoto& Shinohara, Mari L.. 2013. NLRP3 Inflammasome and MSEAE. Autoimmune Diseases،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-503969
Modern Language Association (MLA)
Inoue, Makoto& Shinohara, Mari L.. NLRP3 Inflammasome and MSEAE. Autoimmune Diseases No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-503969
American Medical Association (AMA)
Inoue, Makoto& Shinohara, Mari L.. NLRP3 Inflammasome and MSEAE. Autoimmune Diseases. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-503969
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-503969
