![](/images/graphics-bg.png)
Application of Different Analytical Techniques and Microbiological Assays for the Analysis of Macrolide Antibiotics from Pharmaceutical Dosage Forms and Biological Matrices
Joint Authors
Bekele, Lantider Kassaye
Gebeyehu, Getachew Genete
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-22
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Macrolides are a group of drugs whose activity stems from the presence of a macrolide ring, a large macrocyclic lactone ring to which one or more deoxy sugars may be attached.
They are produced by Streptomyces species and used primarily against gram-positive bacteria.
The determination of antibiotics, including macrolides, is mainly carried out by microbiological assays.
However, microbiological assays tended to lack specificity.
And hence to overcome this problem, lots of chemical and instrumental methods have been developed to determine macrolides separately as well as simultaneously.
Different chromatographic, spectrophotometric, and electrochemical methods used for the determination of macrolides have been reviewed in this paper.
American Psychological Association (APA)
Bekele, Lantider Kassaye& Gebeyehu, Getachew Genete. 2012. Application of Different Analytical Techniques and Microbiological Assays for the Analysis of Macrolide Antibiotics from Pharmaceutical Dosage Forms and Biological Matrices. ISRN Analytical Chemistry،Vol. 2012, no. 2012, pp.1-17.
https://search.emarefa.net/detail/BIM-504006
Modern Language Association (MLA)
Bekele, Lantider Kassaye& Gebeyehu, Getachew Genete. Application of Different Analytical Techniques and Microbiological Assays for the Analysis of Macrolide Antibiotics from Pharmaceutical Dosage Forms and Biological Matrices. ISRN Analytical Chemistry No. 2012 (2012), pp.1-17.
https://search.emarefa.net/detail/BIM-504006
American Medical Association (AMA)
Bekele, Lantider Kassaye& Gebeyehu, Getachew Genete. Application of Different Analytical Techniques and Microbiological Assays for the Analysis of Macrolide Antibiotics from Pharmaceutical Dosage Forms and Biological Matrices. ISRN Analytical Chemistry. 2012. Vol. 2012, no. 2012, pp.1-17.
https://search.emarefa.net/detail/BIM-504006
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-504006