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Improvement of Type 2 Diabetes Mellitus in Obese and Non-Obese Patients after the Duodenal Switch Operation
Joint Authors
Konrad Karcz, Wojciech
Kuesters, S.
Frenken, M.
Grueneberger, J. M.
Cho, E. Y.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-03
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Introduction.
Type 2 diabetes mellitus (T2DM) is one of the most important obesity-related comorbidities.
This study was undertaken to characterise the effect of the biliopancreatic diversion with duodenal switch (BPD-DS) in morbidly obese and nonmorbidly obese diabetic patients.
Methods.
Outcome of 74 obese diabetic patients after BPD-DS and 16 non-obese diabetic patients after BPD or gastric bypass surgery was evaluated.
Insulin usage, HbA1c-levels, and index of HOMA-IR (homeostasis model assessment of insulin resistence) were measured.
Results.
A substantial fraction of patients is free of insulin and shows an improved insulin sensitivity early after the operation, another fraction gets free of insulin in a 12-month period after the operation and a small fraction of long-term insulin users will not get free of insulin but nevertheless shows an improved metabolic status (less insulin needed, normal HbA1c-levels).
Conclusion.
BPD-DS leads to an improvement of T2DM in obese and non-obese patients.
Nevertheless, more data is needed to clarify indications and mechanisms of action and to adjust our operation techniques to the needs of non-obese diabetic patients.
American Psychological Association (APA)
Frenken, M.& Cho, E. Y.& Konrad Karcz, Wojciech& Grueneberger, J. M.& Kuesters, S.. 2011. Improvement of Type 2 Diabetes Mellitus in Obese and Non-Obese Patients after the Duodenal Switch Operation. Journal of Obesity،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-504054
Modern Language Association (MLA)
Frenken, M.…[et al.]. Improvement of Type 2 Diabetes Mellitus in Obese and Non-Obese Patients after the Duodenal Switch Operation. Journal of Obesity No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-504054
American Medical Association (AMA)
Frenken, M.& Cho, E. Y.& Konrad Karcz, Wojciech& Grueneberger, J. M.& Kuesters, S.. Improvement of Type 2 Diabetes Mellitus in Obese and Non-Obese Patients after the Duodenal Switch Operation. Journal of Obesity. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-504054
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-504054