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A Rare Cause of Secondary Amyloidosis : Common Variable Immunodeficiency Disease
Joint Authors
Yılmaz, Zülfükar
Yıldırım, M. Serdar
Kayabaşı, Hasan
Avcı, Yahya
Yılmaz, M. Emin
Yıldırım, Yaşar
Kadiroğlu, Ali Kemal
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-28
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
The common variable immunodeficiency disease (CVID) is the most common symptomatic primary antibody deficiency.
It is the most frequently observed cause of panhypogammaglobulinemia in adults.
Here, we present a case of systemic amyloidosis that developed secondary to the common variable immunodeficiency disease causing recurrent infections in a young female patient.
A 24-year-old female patient, who was under treatment at the gynecology and obstetrics clinic for pelvic inflammatory disease, was referred to our clinic when she was observed to have swellings in her legs, hands, and face.
She had proteinuria at a rate of 3.5 gr/day, and her serum albumin was 1.5 gr/dl.
The levels of immunoglobulins are IgG: 138 mg/dl, IgA: 22,6 mg/dl, and IgM: 16,8 mg/dl.
The renal USG revealed that the kidneys were observed to be enlarged.
Since the patient had recurrent infections, hypogammaglobulinemia, nephrotic range proteinuria, and enlarged kidneys in the renal USG, she was thought to have type AA amyloidosis and therefore underwent a renal biopsy.
The kidney biopsy revealed amyloid (+).
So the patient was diagnosed with AA type of amyloidosis secondary to common variable immunodeficiency disease.
A treatment regimen (an ACE inhibitor and a statin) with monthly administration of intravenous immunoglobulin was started.
American Psychological Association (APA)
Kadiroğlu, Ali Kemal& Yıldırım, Yaşar& Yılmaz, Zülfükar& Kayabaşı, Hasan& Avcı, Yahya& Yıldırım, M. Serdar…[et al.]. 2012. A Rare Cause of Secondary Amyloidosis : Common Variable Immunodeficiency Disease. Case Reports in Nephrology،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-504058
Modern Language Association (MLA)
Kadiroğlu, Ali Kemal…[et al.]. A Rare Cause of Secondary Amyloidosis : Common Variable Immunodeficiency Disease. Case Reports in Nephrology No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-504058
American Medical Association (AMA)
Kadiroğlu, Ali Kemal& Yıldırım, Yaşar& Yılmaz, Zülfükar& Kayabaşı, Hasan& Avcı, Yahya& Yıldırım, M. Serdar…[et al.]. A Rare Cause of Secondary Amyloidosis : Common Variable Immunodeficiency Disease. Case Reports in Nephrology. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-504058
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-504058