Significance of Image Guidance to Clinical Outcomes for Localized Prostate Cancer
Joint Authors
Gao, Hong
Xiu, Xia
Wu, Qinhong
Li, Ming
Li, Gaofeng
Xu, Yonggang
Zhong, Qiuzi
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-10
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
To compare toxicity profiles and biochemical tumor control outcomes between patients treated with image-guided intensity-modulated radiotherapy (IG-IMRT) and non-IGRT intensity-modulated radiotherapy (IMRT) for clinically localized prostate cancer.
Materials and Methods.
Between 2009 and 2012, 65 patients with localized prostate cancer were treated with IG-IMRT.
This group of patients was retrospectively compared with a similar cohort of 62 patients who were treated between 2004 and 2009 with IMRT to the same dose without image guidance.
Results.
The median follow-up time was 4.8 years.
The rectal volume receiving ≥40 and ≥70 Gy was significantly lower in the IG-IMRT group.
Grade 2 and higher acute and late GI and GU toxicity rates were lower in IG-IMRT group, but there was no statistical difference.
No significant improvement in biochemical control at 5 years was observed in two groups.
In a Cox regression analysis identifying predictors for PSA relapse-free survival, only preradiotherapy PSA was significantly associated with biochemical control; IG-IMRT was not a statistically significant indicator.
Conclusions.
The use of image guidance in the radiation of prostate cancer at our institute did not show significant reduction in the rates of GI and GU toxicity and did not improve the biochemical control compared with IMRT.
American Psychological Association (APA)
Zhong, Qiuzi& Gao, Hong& Li, Gaofeng& Xiu, Xia& Wu, Qinhong& Li, Ming…[et al.]. 2014. Significance of Image Guidance to Clinical Outcomes for Localized Prostate Cancer. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-504109
Modern Language Association (MLA)
Zhong, Qiuzi…[et al.]. Significance of Image Guidance to Clinical Outcomes for Localized Prostate Cancer. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-504109
American Medical Association (AMA)
Zhong, Qiuzi& Gao, Hong& Li, Gaofeng& Xiu, Xia& Wu, Qinhong& Li, Ming…[et al.]. Significance of Image Guidance to Clinical Outcomes for Localized Prostate Cancer. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-504109
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-504109