Visceral Leishmaniasis with Associated Common, Uncommon, and Atypical Morphological Features on Bone Marrow Aspirate Cytology in Nonendemic Region
Joint Authors
Kaushik, Rajeev Mohan
Chandra, Smita
Chandra, Harish
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-08
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objectives.
The present study was conducted to categorise the morphological features on bone marrow aspirate cytology into common, uncommon, and atypical features in a nonendemic region which would be helpful in clinching an early and correct diagnosis especially in clinically unsuspected cases.
Methods.
The morphological features on bone marrow were categorized into common, uncommon, and atypical in cases of leishmaniasis from non endemic region.
Results.
Out of total 27 cases, 77.7% were residents of places at the height of 500 m or above and fever was the most common presentation followed by hepatosplenomegaly.
Plasmacytosis, hemophagocytosis were the common cytological features while dysmyelopoiesis, presence of leishmania bodies in nonhistiocytic cells, and granuloma with necrosis were uncommon features.
Aggregates of LD bodies in form of ring, floret, or strap shapes along with giant cells constitute the atypical morphological features.
Conclusion.
The knowledge of common, uncommon, and atypical features on bone marrow aspirate cytology is helpful in clinching an early and correct diagnosis of leishmaniasis especially in non endemic areas where clinical suspicion is low.
These features will guide the pathologist for vigilant search of LD bodies in the marrow for definite diagnosis and thus will also be helpful in preventing unnecessary workups.
American Psychological Association (APA)
Chandra, Harish& Chandra, Smita& Kaushik, Rajeev Mohan. 2013. Visceral Leishmaniasis with Associated Common, Uncommon, and Atypical Morphological Features on Bone Marrow Aspirate Cytology in Nonendemic Region. Journal of Tropical Medicine،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-504144
Modern Language Association (MLA)
Chandra, Harish…[et al.]. Visceral Leishmaniasis with Associated Common, Uncommon, and Atypical Morphological Features on Bone Marrow Aspirate Cytology in Nonendemic Region. Journal of Tropical Medicine No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-504144
American Medical Association (AMA)
Chandra, Harish& Chandra, Smita& Kaushik, Rajeev Mohan. Visceral Leishmaniasis with Associated Common, Uncommon, and Atypical Morphological Features on Bone Marrow Aspirate Cytology in Nonendemic Region. Journal of Tropical Medicine. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-504144
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-504144