The Asthma-COPD Overlap Syndrome : A Common Clinical Problem in the Elderly
Joint Authors
Albertson, Timothy E.
Schivo, Michael
Zeki, Amir A.
Chan, Andrew
Louie, Samuel
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-30
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Many patients with breathlessness and chronic obstructive lung disease are diagnosed with either asthma, COPD, or—frequently—mixed disease.
More commonly, patients with uncharacterized breathlessness are treated with therapies that target asthma and COPD rather than one of these diseases.
This common practice represents the difficulty in distinguishing these disorders clinically, particularly in patients with a history that does not easily differentiate asthma from COPD.
A common clinical scenario is an older former smoker with partially reversible or fixed airflow obstruction and evidence of atopy, demonstrating “overlap” features of asthma and COPD.
We stress that asthma-COPD overlap syndrome becomes more prevalent with advancing age as patients respond less favorably to guideline-recommended drug therapy.
We review the similarities and differences in clinical characteristics between these disorders, and their physiologic and inflammatory profiles within the context of the aging patient.
We underscore the difficulties in differentiating asthma from COPD in current or former smokers, share our institutional experience with overlap syndrome, and highlight the need for new research to better characterize and investigate this important clinical phenotype.
American Psychological Association (APA)
Zeki, Amir A.& Schivo, Michael& Chan, Andrew& Albertson, Timothy E.& Louie, Samuel. 2011. The Asthma-COPD Overlap Syndrome : A Common Clinical Problem in the Elderly. Journal of Allergy،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-504235
Modern Language Association (MLA)
Zeki, Amir A.…[et al.]. The Asthma-COPD Overlap Syndrome : A Common Clinical Problem in the Elderly. Journal of Allergy No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-504235
American Medical Association (AMA)
Zeki, Amir A.& Schivo, Michael& Chan, Andrew& Albertson, Timothy E.& Louie, Samuel. The Asthma-COPD Overlap Syndrome : A Common Clinical Problem in the Elderly. Journal of Allergy. 2011. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-504235
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-504235