Evaluation of a Novel Rapid Test System for the Detection of Specific IgE to Hymenoptera Venoms
Joint Authors
Jakob, Thilo
Offermann, Nadine
Fooke, Margrit
Schulte-Pelkum, Johannes
Pfender, Nikolai
Lucassen, Ralf
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-27
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
The Allergy Lateral Flow Assay (ALFA) is a novel rapid assay for the detection of sIgE to allergens.
The objective of this study is the evaluation of ALFA for the detection of sIgE to bee venom (BV) and wasp venom (WV) in insect venom allergic patients.
Methods.
Specific IgE to BV and WV was analyzed by ALFA, ALLERG-O-LIQ, and ImmunoCAP in 80 insect venom allergic patients and 60 control sera.
Sensitivity and specificity of ALFA and correlation of ALFA and ImmunoCAP results were calculated.
Results.
The sensitivity/specificity of ALFA to the diagnosis was 100%/83% for BV and 82%/97% for WV.
For insect venom allergic patients, the Spearman correlation coefficient for ALFA versus ImmunoCAP was 0.79 for BV and 0.80 for WV.
However, significant differences in the negative control groups were observed.
Conclusion.
ALFA represents a simple, robust, and reliable tool for the rapid detection of sIgE to insect venoms.
American Psychological Association (APA)
Pfender, Nikolai& Lucassen, Ralf& Offermann, Nadine& Schulte-Pelkum, Johannes& Fooke, Margrit& Jakob, Thilo. 2012. Evaluation of a Novel Rapid Test System for the Detection of Specific IgE to Hymenoptera Venoms. Journal of Allergy،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-504244
Modern Language Association (MLA)
Pfender, Nikolai…[et al.]. Evaluation of a Novel Rapid Test System for the Detection of Specific IgE to Hymenoptera Venoms. Journal of Allergy No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-504244
American Medical Association (AMA)
Pfender, Nikolai& Lucassen, Ralf& Offermann, Nadine& Schulte-Pelkum, Johannes& Fooke, Margrit& Jakob, Thilo. Evaluation of a Novel Rapid Test System for the Detection of Specific IgE to Hymenoptera Venoms. Journal of Allergy. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-504244
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-504244