Where Do AQP4 Antibodies Fit in the Pathogenesis of NMO?
Joint Authors
Nakatsuji, Yuji
Kinoshita, Makoto
Source
Multiple Sclerosis International
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Recent advances in the field of neuromyelitis optica (NMO) research provided convincing evidence that anti-AQP4 antibody (AQP4-Ab) not only serves as a highly specific disease marker, but also plays an essential role in the pathogenesis of the disease.
Although it is now widely recognized that AQP4-Ab induces astrocytic necrosis in a complement-dependent manner, additional triggers are also suspected as a prerequisite for the development of the disease.
Unraveling these unresolved aspects of the disease will provide substantial insight into still controversial issues in the pathogenesis of NMO.
American Psychological Association (APA)
Kinoshita, Makoto& Nakatsuji, Yuji. 2012. Where Do AQP4 Antibodies Fit in the Pathogenesis of NMO?. Multiple Sclerosis International،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-504259
Modern Language Association (MLA)
Kinoshita, Makoto& Nakatsuji, Yuji. Where Do AQP4 Antibodies Fit in the Pathogenesis of NMO?. Multiple Sclerosis International No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-504259
American Medical Association (AMA)
Kinoshita, Makoto& Nakatsuji, Yuji. Where Do AQP4 Antibodies Fit in the Pathogenesis of NMO?. Multiple Sclerosis International. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-504259
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-504259
