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Value of Histopathologic Examination of Uterine Products after First-Trimester Miscarriage
Author
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-06-26
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The main rationale of routine histopathologic examination of products after first-trimester miscarriages is to detect an ectopic pregnancy or a molar pregnancy, which require further management.
An alternative approach is to examine the products only when there is a definite indication.
As there is no agreement, we aimed to study whether routine histopathological examination of tissues obtained after first-trimester miscarriage is of any clinical value in our populations.
Medical records of all (558) patients with a diagnosis of first-trimester miscarriage over 4 years (2007–2010) at King Abdulaziz University Hospital, Jeddah, Saudi Arabia, were reviewed.
Histopathologic examination confirmed products of conception in 537 (96.2%) patients, no products of conception in 17 (3%) patients, molar pregnancy in 2 (0.4%) patients, and decidual tissues without chorionic villi (Arias-Stella reaction) in 2 (0.4%) patients.
After clinical correlation, only one unsuspected partial molar pregnancy was diagnosed by histopathology examination.
Conclusion is that it does not appear reasonable to perform histopathological examination routinely after all first-trimester miscarriages in our studied population.
We recommend that histopathological examination be performed in select instances: when the diagnosis is uncertain, when fewer tissues have been obtained during surgery, when unexpected pathology was seen, when ultrasound suggests a molar pregnancy, or when patients are considered at high risk for trophoblastic disease.
American Psychological Association (APA)
Alsibiani, Sharifa Ali. 2014. Value of Histopathologic Examination of Uterine Products after First-Trimester Miscarriage. BioMed Research International،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-504383
Modern Language Association (MLA)
Alsibiani, Sharifa Ali. Value of Histopathologic Examination of Uterine Products after First-Trimester Miscarriage. BioMed Research International No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-504383
American Medical Association (AMA)
Alsibiani, Sharifa Ali. Value of Histopathologic Examination of Uterine Products after First-Trimester Miscarriage. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-504383
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-504383