Endothelial Cell Markers in Patients with Pseudoexfoliation Syndrome
Joint Authors
Stafiej, Joanna
Malukiewicz, Grażyna
Rość, Danuta
Lesiewska-Junk, Hanna
Kaźmierczak, Karolina
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-19
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
The aim of the study was the assessment of the von Willebrand antigen (vWF Ag), E-selectin, and P-selectin concentration in blood plasma of patients with pseudoexfoliation syndrome (PEX).
The group studied comprised 30 patients with PEX, aged from 50 to 86 years (mean 73, SD ± 8 years).
Patients with cardiovascular and cerebrovascular diseases, diabetes mellitus, infectious disease, cancer, renal or liver insufficiency, connective tissue disease, current smoking, and hormone, antiplatelet, hypolipidemic, antioxidant, or antihypertensive drug therapy were excluded from the study.
Each subject underwent a complete ophthalmological examination.
Venous blood samples from the cubital vein were taken into sodium citrate solution.
VWF Ag, sP-selectin, and sE-selectin concentration were determined by a commercially available enzyme-linked immunosorbent assay (MedSystems, Diagnostica Stago/Roche, R&D).
Concentrations of vWF Ag, soluble E-selectin, and soluble P-selectin in blood plasma in the study group were compared with the levels in blood plasma in the control group.
No significant differences were found between the groups.
Our results indicate that there might be no correlation between PEX and such endothelial cell markers as vWF Ag, sP-selectin, and sE-selectin concentrations.
Since the study size is limited, further investigations to confirm that there is no association between endothelial dysfunction in PEX and risk of future cardiovascular disease are necessary.
American Psychological Association (APA)
Stafiej, Joanna& Malukiewicz, Grażyna& Lesiewska-Junk, Hanna& Rość, Danuta& Kaźmierczak, Karolina. 2012. Endothelial Cell Markers in Patients with Pseudoexfoliation Syndrome. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-504438
Modern Language Association (MLA)
Stafiej, Joanna…[et al.]. Endothelial Cell Markers in Patients with Pseudoexfoliation Syndrome. The Scientific World Journal No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-504438
American Medical Association (AMA)
Stafiej, Joanna& Malukiewicz, Grażyna& Lesiewska-Junk, Hanna& Rość, Danuta& Kaźmierczak, Karolina. Endothelial Cell Markers in Patients with Pseudoexfoliation Syndrome. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-504438
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-504438