Pharmacogenetics of Chronic Pain and Its Treatment

Joint Authors

Hronová, Karolína
Světlík, Svatopluk
Matoušková, Olga
Bakhouche, Hana
Slanař, Ondřej

Source

Mediators of Inflammation

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-23, 23 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-05-20

Country of Publication

Egypt

No. of Pages

23

Main Subjects

Diseases

Abstract EN

This paper reviews the impact of genetic variability of drug metabolizing enzymes, transporters, receptors, and pathways involved in chronic pain perception on the efficacy and safety of analgesics and other drugs used for chronic pain treatment.

Several candidate genes have been identified in the literature, while there is usually only limited clinical evidence substantiating for the penetration of the testing for these candidate biomarkers into the clinical practice.

Further, the pain-perception regulation and modulation are still not fully understood, and thus more complex knowledge of genetic and epigenetic background for analgesia will be needed prior to the clinical use of the candidate genetic biomarkers.

American Psychological Association (APA)

Světlík, Svatopluk& Hronová, Karolína& Bakhouche, Hana& Matoušková, Olga& Slanař, Ondřej. 2013. Pharmacogenetics of Chronic Pain and Its Treatment. Mediators of Inflammation،Vol. 2013, no. 2013, pp.1-23.
https://search.emarefa.net/detail/BIM-504476

Modern Language Association (MLA)

Světlík, Svatopluk…[et al.]. Pharmacogenetics of Chronic Pain and Its Treatment. Mediators of Inflammation No. 2013 (2013), pp.1-23.
https://search.emarefa.net/detail/BIM-504476

American Medical Association (AMA)

Světlík, Svatopluk& Hronová, Karolína& Bakhouche, Hana& Matoušková, Olga& Slanař, Ondřej. Pharmacogenetics of Chronic Pain and Its Treatment. Mediators of Inflammation. 2013. Vol. 2013, no. 2013, pp.1-23.
https://search.emarefa.net/detail/BIM-504476

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-504476