Pharmacogenetics of Chronic Pain and Its Treatment
Joint Authors
Hronová, Karolína
Světlík, Svatopluk
Matoušková, Olga
Bakhouche, Hana
Slanař, Ondřej
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-23, 23 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-05-20
Country of Publication
Egypt
No. of Pages
23
Main Subjects
Abstract EN
This paper reviews the impact of genetic variability of drug metabolizing enzymes, transporters, receptors, and pathways involved in chronic pain perception on the efficacy and safety of analgesics and other drugs used for chronic pain treatment.
Several candidate genes have been identified in the literature, while there is usually only limited clinical evidence substantiating for the penetration of the testing for these candidate biomarkers into the clinical practice.
Further, the pain-perception regulation and modulation are still not fully understood, and thus more complex knowledge of genetic and epigenetic background for analgesia will be needed prior to the clinical use of the candidate genetic biomarkers.
American Psychological Association (APA)
Světlík, Svatopluk& Hronová, Karolína& Bakhouche, Hana& Matoušková, Olga& Slanař, Ondřej. 2013. Pharmacogenetics of Chronic Pain and Its Treatment. Mediators of Inflammation،Vol. 2013, no. 2013, pp.1-23.
https://search.emarefa.net/detail/BIM-504476
Modern Language Association (MLA)
Světlík, Svatopluk…[et al.]. Pharmacogenetics of Chronic Pain and Its Treatment. Mediators of Inflammation No. 2013 (2013), pp.1-23.
https://search.emarefa.net/detail/BIM-504476
American Medical Association (AMA)
Světlík, Svatopluk& Hronová, Karolína& Bakhouche, Hana& Matoušková, Olga& Slanař, Ondřej. Pharmacogenetics of Chronic Pain and Its Treatment. Mediators of Inflammation. 2013. Vol. 2013, no. 2013, pp.1-23.
https://search.emarefa.net/detail/BIM-504476
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-504476