Autoimmune Thyroid Disease in Rheumatoid Arthritis : A Global Perspective
Joint Authors
Montoya-Ortiz, Gladys
Rojas-Villarraga, Adriana
Cárdenas Roldán, Jorge
Amaya-Amaya, Jenny
Giraldo-Villamil, Juliana
Mantilla, Rubén D.
Anaya, Juan-Manuel
Cruz-Tapias, Paola
Castellanos-de la Hoz, Juan
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-18
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Objective.
To determine the prevalence and impact of autoimmune thyroid disease (AITD) in patients with rheumatoid arthritis (RA).
Methods.
Eight-hundred patients were included.
The association between AITD and RA was analyzed was analyzed by bivariate and multivariate analysis.
In addition, a literature review was done focusing on geographical variations.
Results.
In our cohort the prevalence of AITD was 9.8% while the presence of antibodies was 37.8% for antithyroperoxidase enzyme (TPOAb) and 20.8% for antithyroglobulin protein (TgAb).
The presence of type 2 diabetes, thrombosis, abnormal body mass index, and a high educational level was positively associated with AITD.
The literature review disclosed a geographical variation of AITD in RA ranging from 0.5% to 27%.
Autoantibody prevalence ranges from 6% to 31% for TgAb, 5% to 37% for TPOAb, and from 11.4% to 32% for the presence of either of the two.
Conclusion.
AITD is not uncommon in RA and should be systematically assessed since it is a risk factor for developing diabetes and cardiovascular disease.
These results may help to further study the common mechanisms of autoimmune diseases, to improve patients’ outcome, and to define public health policies.
An international consensus to accurately diagnose AITD is warranted.
American Psychological Association (APA)
Cárdenas Roldán, Jorge& Amaya-Amaya, Jenny& Castellanos-de la Hoz, Juan& Giraldo-Villamil, Juliana& Montoya-Ortiz, Gladys& Cruz-Tapias, Paola…[et al.]. 2012. Autoimmune Thyroid Disease in Rheumatoid Arthritis : A Global Perspective. Arthritis،Vol. 2012, no. 2012, pp.1-15.
https://search.emarefa.net/detail/BIM-504526
Modern Language Association (MLA)
Cárdenas Roldán, Jorge…[et al.]. Autoimmune Thyroid Disease in Rheumatoid Arthritis : A Global Perspective. Arthritis No. 2012 (2012), pp.1-15.
https://search.emarefa.net/detail/BIM-504526
American Medical Association (AMA)
Cárdenas Roldán, Jorge& Amaya-Amaya, Jenny& Castellanos-de la Hoz, Juan& Giraldo-Villamil, Juliana& Montoya-Ortiz, Gladys& Cruz-Tapias, Paola…[et al.]. Autoimmune Thyroid Disease in Rheumatoid Arthritis : A Global Perspective. Arthritis. 2012. Vol. 2012, no. 2012, pp.1-15.
https://search.emarefa.net/detail/BIM-504526
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-504526