Chitosan-Grafted Copolymers and Chitosan-Ligand Conjugates as Matrices for Pulmonary Drug Delivery
Joint Authors
Chiappetta, Diego A.
Sarmento, Bruno
das Neves, José
Sosnik, Alejandro
Goycoolea, Francisco
Andrade, Fernanda
Source
International Journal of Carbohydrate Chemistry
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-04
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Recently, much attention has been given to pulmonary drug delivery by means of nanosized systems to treat both local and systemic diseases.
Among the different materials used for the production of nanocarriers, chitosan enjoys high popularity due to its inherent characteristics such as biocompatibility, biodegradability, and mucoadhesion, among others.
Through the modification of chitosan chemical structure, either by the addition of new chemical groups or by the functionalization with ligands, it is possible to obtain derivatives with advantageous and specific characteristics for pulmonary administration.
In this paper, we discuss the advantages of using chitosan for nanotechnology-based pulmonary delivery of drugs and summarize the most recent and promising modifications performed to the chitosan molecule in order to improve its characteristics.
American Psychological Association (APA)
Andrade, Fernanda& Goycoolea, Francisco& Chiappetta, Diego A.& das Neves, José& Sosnik, Alejandro& Sarmento, Bruno. 2011. Chitosan-Grafted Copolymers and Chitosan-Ligand Conjugates as Matrices for Pulmonary Drug Delivery. International Journal of Carbohydrate Chemistry،Vol. 2011, no. 2011, pp.1-14.
https://search.emarefa.net/detail/BIM-504593
Modern Language Association (MLA)
Andrade, Fernanda…[et al.]. Chitosan-Grafted Copolymers and Chitosan-Ligand Conjugates as Matrices for Pulmonary Drug Delivery. International Journal of Carbohydrate Chemistry No. 2011 (2011), pp.1-14.
https://search.emarefa.net/detail/BIM-504593
American Medical Association (AMA)
Andrade, Fernanda& Goycoolea, Francisco& Chiappetta, Diego A.& das Neves, José& Sosnik, Alejandro& Sarmento, Bruno. Chitosan-Grafted Copolymers and Chitosan-Ligand Conjugates as Matrices for Pulmonary Drug Delivery. International Journal of Carbohydrate Chemistry. 2011. Vol. 2011, no. 2011, pp.1-14.
https://search.emarefa.net/detail/BIM-504593
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-504593