Thyrotoxic Periodic Paralysis : Case Reports and an Up-to-Date Review of the Literature
Joint Authors
Wlodek, Christina
Lulsegged, Abbi
Rossi, Michela
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-22
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Objectives.
To describe 2 cases of thyrotoxic periodic paralysis.
Methods.
We report of 2 cases of thyrotoxic periodic paralysis in 2 individuals from 2 different backgrounds with emphasis on their presentation and treatment.
We also conducted a literature search to put together an update review of thyrotoxic periodic paralysis.
Results.
A 47-year-old Chinese and 28-year-old Caucasian male presented with profound yet reversible weakness associated with hypokalemia on admission bloods and thyrotoxicosis.
Both were given definitive therapy to prevent recurrence of attacks with any future relapse of thyrotoxicosis.
Conclusion.
Thyrotoxic periodic paralysis (TPP) is a rare but potentially serious complication of thyrotoxicosis resulting in temporary but severe muscle weakness.
Recent discovery of a novel mutation in the KCNJ18 gene which codes for an inwardly rectifying potassium channel and is controlled by thyroid hormones may provide greater insight into the pathogenesis of TPP.
American Psychological Association (APA)
Lulsegged, Abbi& Wlodek, Christina& Rossi, Michela. 2011. Thyrotoxic Periodic Paralysis : Case Reports and an Up-to-Date Review of the Literature. Case Reports in Endocrinology،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-504669
Modern Language Association (MLA)
Lulsegged, Abbi…[et al.]. Thyrotoxic Periodic Paralysis : Case Reports and an Up-to-Date Review of the Literature. Case Reports in Endocrinology No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-504669
American Medical Association (AMA)
Lulsegged, Abbi& Wlodek, Christina& Rossi, Michela. Thyrotoxic Periodic Paralysis : Case Reports and an Up-to-Date Review of the Literature. Case Reports in Endocrinology. 2011. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-504669
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-504669