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Autonomic Testing in Functional Gastrointestinal Disorders : Implications of Reproducible Gastrointestinal Complaints during Tilt Table Testing
Joint Authors
O'Riordan, Mary Ann
Chelimsky, Gisela
Chelimsky, Thomas C.
Safder, Shaista
Source
Gastroenterology Research and Practice
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-05-05
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background: The pathophysiology of functional abdominal pain (FAP) is unknown.
The upright portion of a tilt table test triggers typical symptoms in certain children.
Aim: To compare the pathophysiology and treatment response of children with FAP whose gastrointestinal symptoms (GI) were replicated (RGI) by tilt table testing (TTT) to those in whom TTT did not have this effect (NRGI).
Methods: An IRB-approved retrospective review of the autonomic laboratory database identified all children tested for GI complaints.
We compared results of TTT, Valsalva maneuver, deep breathing and the axon reflex sweat test.
Overall treatment response and that specific to fludrocortisone was ranked from 1 to 5, with 1 “much worse,” 3 “neutral,” and 5 “much better.” Results: 32/76 identified children had reproducible symptoms on TTT (RGI) and 44 did not (NRGI).
The RGI group was younger, had a shorter duration of symptoms, more postural tachycardia syndrome (POTS) and benefited more from fludrocortisone (73% in RGI vs.
25% in NRGI).
Conclusion: Dividing patients with FAP according to the effect of TTT on their symptoms appears to delineate 2 fundamentally different groups, with potentially different pathophysiologies and treatment responses.
A prospective study is needed.
American Psychological Association (APA)
Safder, Shaista& Chelimsky, Thomas C.& O'Riordan, Mary Ann& Chelimsky, Gisela. 2009. Autonomic Testing in Functional Gastrointestinal Disorders : Implications of Reproducible Gastrointestinal Complaints during Tilt Table Testing. Gastroenterology Research and Practice،Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-504762
Modern Language Association (MLA)
Safder, Shaista…[et al.]. Autonomic Testing in Functional Gastrointestinal Disorders : Implications of Reproducible Gastrointestinal Complaints during Tilt Table Testing. Gastroenterology Research and Practice No. 2009 (2009), pp.1-6.
https://search.emarefa.net/detail/BIM-504762
American Medical Association (AMA)
Safder, Shaista& Chelimsky, Thomas C.& O'Riordan, Mary Ann& Chelimsky, Gisela. Autonomic Testing in Functional Gastrointestinal Disorders : Implications of Reproducible Gastrointestinal Complaints during Tilt Table Testing. Gastroenterology Research and Practice. 2009. Vol. 2009, no. 2009, pp.1-6.
https://search.emarefa.net/detail/BIM-504762
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-504762