Neuropeptide Y in the Adult and Fetal Human Pineal Gland
Joint Authors
Møller, Morten
Phansuwan-Pujito, Pansiri
Badiu, Corin
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-17
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Neuropeptide Y was isolated from the porcine brain in 1982 and shown to be colocalized with noradrenaline in sympathetic nerve terminals.
The peptide has been demonstrated to be present in sympathetic nerve fibers innervating the pineal gland in many mammalian species.
In this investigation, we show by use of immunohistochemistry that neuropeptide Y is present in nerve fibers of the adult human pineal gland.
The fibers are classical neuropeptidergic fibers endowed with large boutons en passage and primarily located in a perifollicular position with some fibers entering the pineal parenchyma inside the follicle.
The distance from the immunoreactive terminals to the pinealocytes indicates a modulatory function of neuropeptide Y for pineal physiology.
Some of the immunoreactive fibers might originate from neurons located in the brain and be a part of the central innervation of the pineal gland.
In a series of human fetuses, neuropeptide Y-containing nerve fibers was present and could be detected as early as in the pineal of four- to five-month-old fetuses.
This early innervation of the human pineal is different from most rodents, where the innervation starts postnatally.
American Psychological Association (APA)
Møller, Morten& Phansuwan-Pujito, Pansiri& Badiu, Corin. 2014. Neuropeptide Y in the Adult and Fetal Human Pineal Gland. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-504768
Modern Language Association (MLA)
Møller, Morten…[et al.]. Neuropeptide Y in the Adult and Fetal Human Pineal Gland. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-504768
American Medical Association (AMA)
Møller, Morten& Phansuwan-Pujito, Pansiri& Badiu, Corin. Neuropeptide Y in the Adult and Fetal Human Pineal Gland. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-504768
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-504768