![](/images/graphics-bg.png)
Heavy Metal Poisoning and Cardiovascular Disease
Joint Authors
Alissa, Eman M.
Ferns, Gordon A. A.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-21, 21 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-08
Country of Publication
Egypt
No. of Pages
21
Main Subjects
Pharmacy, Health & Medical Sciences
Medicine
Abstract EN
Cardiovascular disease (CVD) is an increasing world health problem.
Traditional risk factors fail to account for all deaths from CVD.
It is mainly the environmental, dietary and lifestyle behavioral factors that are the control keys in the progress of this disease.
The potential association between chronic heavy metal exposure, like arsenic, lead, cadmium, mercury, and CVD has been less well defined.
The mechanism through which heavy metals act to increase cardiovascular risk factors may act still remains unknown, although impaired antioxidants metabolism and oxidative stress may play a role.
However, the exact mechanism of CVD induced by heavy metals deserves further investigation either through animal experiments or through molecular and cellular studies.
Furthermore, large-scale prospective studies with follow up on general populations using appropriate biomarkers and cardiovascular endpoints might be recommended to identify the factors that predispose to heavy metals toxicity in CVD.
In this review, we will give a brief summary of heavy metals homeostasis, followed by a description of the available evidence for their link with CVD and the proposed mechanisms of action by which their toxic effects might be explained.
Finally, suspected interactions between genetic, nutritional and environmental factors are discussed.
American Psychological Association (APA)
Alissa, Eman M.& Ferns, Gordon A. A.. 2011. Heavy Metal Poisoning and Cardiovascular Disease. Journal of Toxicology،Vol. 2011, no. 2011, pp.1-21.
https://search.emarefa.net/detail/BIM-504882
Modern Language Association (MLA)
Alissa, Eman M.& Ferns, Gordon A. A.. Heavy Metal Poisoning and Cardiovascular Disease. Journal of Toxicology No. 2011 (2011), pp.1-21.
https://search.emarefa.net/detail/BIM-504882
American Medical Association (AMA)
Alissa, Eman M.& Ferns, Gordon A. A.. Heavy Metal Poisoning and Cardiovascular Disease. Journal of Toxicology. 2011. Vol. 2011, no. 2011, pp.1-21.
https://search.emarefa.net/detail/BIM-504882
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-504882