The Role of Fluorine-18-fluorodeoxyglucose Positron Emission Tomography in Assessing the Response to Neoadjuvant Treatment in Patients with Osteosarcoma
Joint Authors
Treglia, Giorgio
Isgrò, Maria Antonietta
Salsano, Marco
Caldarella, Carmelo
Source
International Journal of Molecular Imaging
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-13
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Aim.
The objective of this study is to systematically review the role of positron emission tomography (PET) and PET/computed tomography (PET/CT) with fluorine-18-fluorodeoxyglucose (FDG) in assessing the response to neoadjuvant treatment in patients with osteosarcoma (OS).
Methods.
A comprehensive literature search of published studies through March 2012 in PubMed/MEDLINE, Embase, and Scopus databases regarding whole-body FDG-PET and FDG-PET/CT in patients with OS was performed.
Results.
Twenty-two studies have investigated the role of FDG-PET and FDG-PET/CT in the evaluation of response to neoadjuvant treatment with either chemotherapy or radiation therapy in patients with OS.
The main findings of these studies are presented.
Conclusion.
FDG-PET or PET/CT seems to be sensitive and reliable diagnostic tools in the assessment of metabolic response to treatment in patients with OS, after baseline PET evaluation has been performed in advance.
However, false positive findings due to inflammation in sites of tumoral response should be considered.
American Psychological Association (APA)
Caldarella, Carmelo& Salsano, Marco& Isgrò, Maria Antonietta& Treglia, Giorgio. 2012. The Role of Fluorine-18-fluorodeoxyglucose Positron Emission Tomography in Assessing the Response to Neoadjuvant Treatment in Patients with Osteosarcoma. International Journal of Molecular Imaging،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-504898
Modern Language Association (MLA)
Caldarella, Carmelo…[et al.]. The Role of Fluorine-18-fluorodeoxyglucose Positron Emission Tomography in Assessing the Response to Neoadjuvant Treatment in Patients with Osteosarcoma. International Journal of Molecular Imaging No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-504898
American Medical Association (AMA)
Caldarella, Carmelo& Salsano, Marco& Isgrò, Maria Antonietta& Treglia, Giorgio. The Role of Fluorine-18-fluorodeoxyglucose Positron Emission Tomography in Assessing the Response to Neoadjuvant Treatment in Patients with Osteosarcoma. International Journal of Molecular Imaging. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-504898
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-504898