![](/images/graphics-bg.png)
Lack of Anatomical Concordance between Preablation and Postablation CT Images : A Risk Factor Related to Ablation Site Recurrence
Joint Authors
Kele, Petra G.
Van der Jagt, Eric J.
de Jong, Koert P.
Krabbe, Paul F. M.
Source
International Journal of Hepatology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-24
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objective.
Variation in the position of the liver between preablation and postablation CT images hampers assessment of treatment of colorectal liver metastasis (CRLM).
The aim of this study was to test the hypothesis that discordant preablation and postablation imaging is associated with more ablation site recurrences (ASRs).
Methods.
Patients with CRLM were included.
Index-tumor size, location, number, RFA approachs and ablative margins were obtained on CT scans.
Preablation and postablation CT images were assigned a “Similarity of Positioning Score” (SiPS).
A suitable cutoff was determined.
Images were classified as identical (SiPS-id) or nonidentical (SiPS-diff).
ASR was identified prospectively on follow-up imaging.
Results.
Forty-seven patients with 97 tumors underwent 64 RFA procedures (39 patients/63 tumors open RFA, 25 patients/34 tumours CT-targeted RFA, 12 patients underwent >1 RFA).
Images of 52 (54%) ablation sites were classified as SiPS-id, 45 (46%) as SiPS-diff.
Index-tumor size, tumor location and number, concomitant partial hepatectomy, and RFA approach did not influence the SiPS.
ASR developed in 11/47 (23%) patients and 20/97 (21%) tumours.
ASR occurred less frequently after open RFA than after CT targeted RFA (P<0.001).
ASR was associated with larger index-tumour size (18.9 versus 12.8 mm, P=0.011).
Cox proportional hazard model confirmed SiPS-diff, index-tumour size >20 mm and CT-targeted RFA as independent risk factors for ASR.
Conclusion.
Variation in anatomical concordance between preablation and postablation images, index-tumor size, and a CT-targeted approach are risk factors for ASR in CRLM.
American Psychological Association (APA)
Kele, Petra G.& Van der Jagt, Eric J.& Krabbe, Paul F. M.& de Jong, Koert P.. 2012. Lack of Anatomical Concordance between Preablation and Postablation CT Images : A Risk Factor Related to Ablation Site Recurrence. International Journal of Hepatology،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-504900
Modern Language Association (MLA)
Kele, Petra G.…[et al.]. Lack of Anatomical Concordance between Preablation and Postablation CT Images : A Risk Factor Related to Ablation Site Recurrence. International Journal of Hepatology No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-504900
American Medical Association (AMA)
Kele, Petra G.& Van der Jagt, Eric J.& Krabbe, Paul F. M.& de Jong, Koert P.. Lack of Anatomical Concordance between Preablation and Postablation CT Images : A Risk Factor Related to Ablation Site Recurrence. International Journal of Hepatology. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-504900
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-504900