Synaptic Remodeling in the Dentate Gyrus, CA3, CA1, Subiculum, and Entorhinal Cortex of Mice : Effects of Deprived Rearing and Voluntary Running
Joint Authors
Schaefers, Andrea T. U.
Teuchert-Noodt, Gertraud
Winter, York
Grafen, Keren
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-05-25
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Hippocampal cell proliferation is strongly increased and synaptic turnover decreased after rearing under social and physical deprivation in gerbils (Meriones unguiculatus).
We examined if a similar epigenetic effect of rearing environment on adult neuroplastic responses can be found in mice (Mus musculus).
We examined synaptic turnover rates in the dentate gyrus, CA3, CA1, subiculum, and entorhinal cortex.
No direct effects of deprived rearing on rates of synaptic turnover were found in any of the studied regions.
However, adult wheel running had the effect of leveling layer-specific differences in synaptic remodeling in the dentate gyrus, CA3, and CA1, but not in the entorhinal cortex and subiculum of animals of both rearing treatments.
Epigenetic effects during juvenile development affected adult neural plasticity in mice, but seemed to be less pronounced than in gerbils.
American Psychological Association (APA)
Schaefers, Andrea T. U.& Grafen, Keren& Teuchert-Noodt, Gertraud& Winter, York. 2010. Synaptic Remodeling in the Dentate Gyrus, CA3, CA1, Subiculum, and Entorhinal Cortex of Mice : Effects of Deprived Rearing and Voluntary Running. Neural Plasticity،Vol. 2010, no. 2010, pp.1-11.
https://search.emarefa.net/detail/BIM-504925
Modern Language Association (MLA)
Schaefers, Andrea T. U.…[et al.]. Synaptic Remodeling in the Dentate Gyrus, CA3, CA1, Subiculum, and Entorhinal Cortex of Mice : Effects of Deprived Rearing and Voluntary Running. Neural Plasticity No. 2010 (2010), pp.1-11.
https://search.emarefa.net/detail/BIM-504925
American Medical Association (AMA)
Schaefers, Andrea T. U.& Grafen, Keren& Teuchert-Noodt, Gertraud& Winter, York. Synaptic Remodeling in the Dentate Gyrus, CA3, CA1, Subiculum, and Entorhinal Cortex of Mice : Effects of Deprived Rearing and Voluntary Running. Neural Plasticity. 2010. Vol. 2010, no. 2010, pp.1-11.
https://search.emarefa.net/detail/BIM-504925
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-504925