Searching for MIND : MicroRNAs in Neurodegenerative Diseases
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-08-23
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
In few years our understanding of microRNA (miRNA) biogenesis, molecular mechanisms by which miRNAs regulate gene expression, and the functional roles of miRNAs has been expanded.
Interestingly, numerous miRNAs are expressed in a spatially and temporally controlled manner in the nervous system, suggesting that their posttrascriptional regulation may be particularly relevant in neural development and function.
MiRNA studies in neurobiology showed their involvement in synaptic plasticity and brain diseases.
In this review ,correlations between miRNA-mediated gene silencing and Alzheimer's, Parkinson's, and other neurodegenerative diseases will be discussed.
Molecular and cellular neurobiological studies of the miRNAs in neurodegeneration represent the exploration of a new Frontier of miRNAs biology and the potential development of new diagnostic tests and genetic therapies for neurodegenerative diseases.
American Psychological Association (APA)
2009. Searching for MIND : MicroRNAs in Neurodegenerative Diseases. Journal of Biomedicine and Biotechnology،Vol. 2009, no. 2009, pp.1-8.
https://search.emarefa.net/detail/BIM-505002
Modern Language Association (MLA)
Searching for MIND : MicroRNAs in Neurodegenerative Diseases. Journal of Biomedicine and Biotechnology No. 2009 (2009), pp.1-8.
https://search.emarefa.net/detail/BIM-505002
American Medical Association (AMA)
Searching for MIND : MicroRNAs in Neurodegenerative Diseases. Journal of Biomedicine and Biotechnology. 2009. Vol. 2009, no. 2009, pp.1-8.
https://search.emarefa.net/detail/BIM-505002
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-505002