Extrahepatic Manifestations and Autoantibodies in Patients with Hepatitis C Virus Infection
Joint Authors
Himoto, Takashi
Masaki, Tsutomu
Source
Clinical and Developmental Immunology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-05
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Patients with chronic hepatitis C virus (HCV) infection frequently have many extrahepatic manifestations, as persistent HCV infection often triggers lymphoproliferative disorders and metabolic abnormalities.
These manifestations primarily include autoimmune disorders such as cryoglobulinemia, Sjögren’s syndrome, and autoimmune thyroid disorders.
It has been well established that chronic HCV infection plays important roles in the production of non-organ-specific autoantibodies, including antinuclear antibodies and smooth muscle antibodies, and organ-specific autoantibodies such as thyroid autoantibodies.
However, the clinical significance of autoantibodies associated with the extrahepatic manifestations caused by HCV infection has not been fully recognized.
In this paper, we mainly focus on the relationship between extrahepatic manifestations and the emergence of autoantibodies in patients with HCV infection and discuss the clinical relevance of the autoantibodies in the extrahepatic disorders.
American Psychological Association (APA)
Himoto, Takashi& Masaki, Tsutomu. 2012. Extrahepatic Manifestations and Autoantibodies in Patients with Hepatitis C Virus Infection. Clinical and Developmental Immunology،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-505013
Modern Language Association (MLA)
Himoto, Takashi& Masaki, Tsutomu. Extrahepatic Manifestations and Autoantibodies in Patients with Hepatitis C Virus Infection. Clinical and Developmental Immunology No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-505013
American Medical Association (AMA)
Himoto, Takashi& Masaki, Tsutomu. Extrahepatic Manifestations and Autoantibodies in Patients with Hepatitis C Virus Infection. Clinical and Developmental Immunology. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-505013
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-505013