Dystrophic Cutaneous Calcification and Metaplastic Bone Formation due to Long Term Bisphosphonate Use in Breast Cancer

Joint Authors

Başsorgun, Cumhur İbrahim
Gunduz, Seyda
Arslan, Deniz
Uysal, Mukremin
Göksu, Sema Sezgin
Tatlı, Ali Murat
Coşkun, Hasan Şenol

Source

Case Reports in Oncological Medicine

Issue

Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-3, 3 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2013-07-15

Country of Publication

Egypt

No. of Pages

3

Main Subjects

Medicine

Abstract EN

Bisphosphonates are widely used in the treatment of breast cancer with bone metastases.

We report a case of a female with breast cancer presented with a rash around a previous mastectomy site and a discharge lesion on her right chest wall in August 2010.

Biopsy of the lesion showed dystrophic calcification and metaplastic bone formation.

The patient’s history revealed a long term use of zoledronic acid for the treatment of breast cancer with bone metastasis.

We stopped the treatment since we believed that the cutaneous dystrophic calcification could be associated with her long term bisphosphonate therapy.

Adverse cutaneous events with bisphosphonates are very rare, and dystrophic calcification has not been reported previously.

The dystrophic calcification and metaplastic bone formation in this patient are thought to be due to long term bisphosphonate usage.

American Psychological Association (APA)

Tatlı, Ali Murat& Gunduz, Seyda& Göksu, Sema Sezgin& Arslan, Deniz& Uysal, Mukremin& Başsorgun, Cumhur İbrahim…[et al.]. 2013. Dystrophic Cutaneous Calcification and Metaplastic Bone Formation due to Long Term Bisphosphonate Use in Breast Cancer. Case Reports in Oncological Medicine،Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-505059

Modern Language Association (MLA)

Tatlı, Ali Murat…[et al.]. Dystrophic Cutaneous Calcification and Metaplastic Bone Formation due to Long Term Bisphosphonate Use in Breast Cancer. Case Reports in Oncological Medicine No. 2013 (2013), pp.1-3.
https://search.emarefa.net/detail/BIM-505059

American Medical Association (AMA)

Tatlı, Ali Murat& Gunduz, Seyda& Göksu, Sema Sezgin& Arslan, Deniz& Uysal, Mukremin& Başsorgun, Cumhur İbrahim…[et al.]. Dystrophic Cutaneous Calcification and Metaplastic Bone Formation due to Long Term Bisphosphonate Use in Breast Cancer. Case Reports in Oncological Medicine. 2013. Vol. 2013, no. 2013, pp.1-3.
https://search.emarefa.net/detail/BIM-505059

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-505059