Glycyrrhizic Acid in the Treatment of Liver Diseases : Literature Review
Joint Authors
Cheng, Gen-hong
Sun, Ming-yu
Liu, Ping
Li, Jian-yuan
Cao, Hong-yan
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-13
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Glycyrrhizic acid (GA) is a triterpene glycoside found in the roots of licorice plants (Glycyrrhiza glabra).
GA is the most important active ingredient in the licorice root, and possesses a wide range of pharmacological and biological activities.
GA coupled with glycyrrhetinic acid and 18-beta-glycyrrhetic acid was developed in China or Japan as an anti-inflammatory, antiviral, and antiallergic drug for liver disease.
This review summarizes the current biological activities of GA and its medical applications in liver diseases.
The pharmacological actions of GA include inhibition of hepatic apoptosis and necrosis; anti-inflammatory and immune regulatory actions; antiviral effects; and antitumor effects.
This paper will be a useful reference for physicians and biologists researching GA and will open the door to novel agents in drug discovery and development from Chinese herbs.
With additional research, GA may be more widely used in the treatment of liver diseases or other conditions.
American Psychological Association (APA)
Li, Jian-yuan& Cao, Hong-yan& Liu, Ping& Cheng, Gen-hong& Sun, Ming-yu. 2014. Glycyrrhizic Acid in the Treatment of Liver Diseases : Literature Review. BioMed Research International،Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-505080
Modern Language Association (MLA)
Li, Jian-yuan…[et al.]. Glycyrrhizic Acid in the Treatment of Liver Diseases : Literature Review. BioMed Research International No. 2014 (2014), pp.1-15.
https://search.emarefa.net/detail/BIM-505080
American Medical Association (AMA)
Li, Jian-yuan& Cao, Hong-yan& Liu, Ping& Cheng, Gen-hong& Sun, Ming-yu. Glycyrrhizic Acid in the Treatment of Liver Diseases : Literature Review. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-15.
https://search.emarefa.net/detail/BIM-505080
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-505080