Molecular Mechanism of Heavy Metal Toxicity and Tolerance in Plants : Central Role of Glutathione in Detoxification of Reactive Oxygen Species and Methylglyoxal and in Heavy Metal Chelation
Joint Authors
Fujita, Masayuki
da Silva, Jaime A. Teixeira
Hossain, Mohammad Anwar
Piyatida, Pukclai
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-37, 37 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-02
Country of Publication
Egypt
No. of Pages
37
Main Subjects
Abstract EN
Heavy metal (HM) toxicity is one of the major abiotic stresses leading to hazardous effects in plants.
A common consequence of HM toxicity is the excessive accumulation of reactive oxygen species (ROS) and methylglyoxal (MG), both of which can cause peroxidation of lipids, oxidation of protein, inactivation of enzymes, DNA damage and/or interact with other vital constituents of plant cells.
Higher plants have evolved a sophisticated antioxidant defense system and a glyoxalase system to scavenge ROS and MG.
In addition, HMs that enter the cell may be sequestered by amino acids, organic acids, glutathione (GSH), or by specific metal-binding ligands.
Being a central molecule of both the antioxidant defense system and the glyoxalase system, GSH is involved in both direct and indirect control of ROS and MG and their reaction products in plant cells, thus protecting the plant from HM-induced oxidative damage.
Recent plant molecular studies have shown that GSH by itself and its metabolizing enzymes—notably glutathione S-transferase, glutathione peroxidase, dehydroascorbate reductase, glutathione reductase, glyoxalase I and glyoxalase II—act additively and coordinately for efficient protection against ROS- and MG-induced damage in addition to detoxification, complexation, chelation and compartmentation of HMs.
The aim of this review is to integrate a recent understanding of physiological and biochemical mechanisms of HM-induced plant stress response and tolerance based on the findings of current plant molecular biology research.
American Psychological Association (APA)
Hossain, Mohammad Anwar& Piyatida, Pukclai& da Silva, Jaime A. Teixeira& Fujita, Masayuki. 2012. Molecular Mechanism of Heavy Metal Toxicity and Tolerance in Plants : Central Role of Glutathione in Detoxification of Reactive Oxygen Species and Methylglyoxal and in Heavy Metal Chelation. Journal of Botany،Vol. 2012, no. 2012, pp.1-37.
https://search.emarefa.net/detail/BIM-505154
Modern Language Association (MLA)
Hossain, Mohammad Anwar…[et al.]. Molecular Mechanism of Heavy Metal Toxicity and Tolerance in Plants : Central Role of Glutathione in Detoxification of Reactive Oxygen Species and Methylglyoxal and in Heavy Metal Chelation. Journal of Botany No. 2012 (2012), pp.1-37.
https://search.emarefa.net/detail/BIM-505154
American Medical Association (AMA)
Hossain, Mohammad Anwar& Piyatida, Pukclai& da Silva, Jaime A. Teixeira& Fujita, Masayuki. Molecular Mechanism of Heavy Metal Toxicity and Tolerance in Plants : Central Role of Glutathione in Detoxification of Reactive Oxygen Species and Methylglyoxal and in Heavy Metal Chelation. Journal of Botany. 2012. Vol. 2012, no. 2012, pp.1-37.
https://search.emarefa.net/detail/BIM-505154
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-505154