Rhus verniciflua Stokes against Advanced Cancer : A Perspective from the Korean Integrative Cancer Center
Joint Authors
Cheon, Seongha
Kim, Sehyun
Jung, Hyunsik
Lee, Sanghun
Kim, Kyungsuk
Lee, Sookyung
Yoon, Seongwoo
Choi, Woncheol
Park, Jaehyun
Eo, Wankyu
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-17
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Active anticancer molecules have been searched from natural products; many drugs were developed from either natural products or their derivatives following the conventional pharmaceutical paradigm of drug discovery.
However, the advances in the knowledge of cancer biology have led to personalized medicine using molecular-targeted agents which create new paradigm.
Clinical benefit is dependent on individual biomarker and overall survival is prolonged through cytostatic rather than cytotoxic effects to cancer cell.
Therefore, a different approach is needed from the single lead compound screening model based on cytotoxicity.
In our experience, the Rhus verniciflua stoke (RVS) extract traditionally used for cancer treatment is beneficial to some advanced cancer patients though it is herbal extract not single compound, and low cytotoxic in vitro.
The standardized RVS extract's action mechanisms as well as clinical outcomes are reviewed here.
We hope that these preliminary results would stimulate different investigation in natural products from conventional chemicals.
American Psychological Association (APA)
Choi, Woncheol& Jung, Hyunsik& Kim, Kyungsuk& Lee, Sookyung& Yoon, Seongwoo& Park, Jaehyun…[et al.]. 2011. Rhus verniciflua Stokes against Advanced Cancer : A Perspective from the Korean Integrative Cancer Center. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-505277
Modern Language Association (MLA)
Choi, Woncheol…[et al.]. Rhus verniciflua Stokes against Advanced Cancer : A Perspective from the Korean Integrative Cancer Center. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-505277
American Medical Association (AMA)
Choi, Woncheol& Jung, Hyunsik& Kim, Kyungsuk& Lee, Sookyung& Yoon, Seongwoo& Park, Jaehyun…[et al.]. Rhus verniciflua Stokes against Advanced Cancer : A Perspective from the Korean Integrative Cancer Center. Journal of Biomedicine and Biotechnology. 2011. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-505277
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-505277