Myasthenia Gravis : A Review
Joint Authors
Jayam-Trouth, Annapurni
Dabi, Alok
Kurukumbi, Mohankumar
Solieman, Noha
Kalyanam, Janaki
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-31
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Acquired myasthenia gravis is a relatively uncommon disorder, with prevalence rates that have increased to about 20 per 100,000 in the US population.
This autoimmune disease is characterized by muscle weakness that fluctuates, worsening with exertion, and improving with rest.
In about two-thirds of the patients, the involvement of extrinsic ocular muscle presents as the initial symptom, usually progressing to involve other bulbar muscles and limb musculature, resulting in generalized myasthenia gravis.
Although the cause of the disorder is unknown, the role of circulating antibodies directed against the nicotinic acetylcholine receptor in its pathogenesis is well established.
As this disorder is highly treatable, prompt recognition is crucial.
During the past decade, significant progress has been made in our understanding of the disease, leading to new treatment modalities and a significant reduction in morbidity and mortality.
American Psychological Association (APA)
Jayam-Trouth, Annapurni& Dabi, Alok& Solieman, Noha& Kurukumbi, Mohankumar& Kalyanam, Janaki. 2012. Myasthenia Gravis : A Review. Autoimmune Diseases،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-505310
Modern Language Association (MLA)
Jayam-Trouth, Annapurni…[et al.]. Myasthenia Gravis : A Review. Autoimmune Diseases No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-505310
American Medical Association (AMA)
Jayam-Trouth, Annapurni& Dabi, Alok& Solieman, Noha& Kurukumbi, Mohankumar& Kalyanam, Janaki. Myasthenia Gravis : A Review. Autoimmune Diseases. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-505310
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-505310