The Sweet Spot : Continued Search for the Glycemic Threshold for Macrovascular Disease—A Retrospective Single Center Experience
Joint Authors
Szpunar, Susan
Moore, Ruth
Boguszewski, Andrzej
Ali, Sajid
Teklinski, Andrew
Desai, Devang
Rosman, Howard
Maciejko, James
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-14
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Atherosclerotic cardiovascular disease (ASCVD) is a common complication of diabetes mellitus and impaired fasting glucose (IFG).
We hypothesized that the relation of fasting glucose levels to ASCVD is linear, with the prevalence of clinical ASCVD beginning to increase even among individuals currently categorized as normoglycemic.
Methods.
Patient charts were retrospectively reviewed from our Dyslipidemic Preventive Cardiology Clinic.
We evaluated the prevalence of ASCVD relative to fasting glucose levels in a cross-section of patients at high risk for ASCVD.
Results.
In 558 dyslipidemic patients, ASCVD prevalence increased with increasing fasting glucose levels.
A significantly higher prevalence of ASCVD was observed among patients with fasting glucose levels between 90 and 99 mg/dL versus lower levels.
As glucose levels increased from 90 to 125 mg/dL, the prevalence of ASCVD continued to rise in parallel.
Logistic regression analysis with forward likelihood ratio stepwise selection indicated that individuals with fasting blood glucose of 90–99 mg/dL were 2.6 times more likely to have ASCVD than those with lower levels of fasting blood glucose.
Conclusion.
Our findings suggest that the current cutoff for impaired fasting glucose of 100 mg/dL may be somewhat conservative and that a level above 90 mg/dL may be more appropriate as an ASCVD risk factor, particularly in patients with a lipid disorder.
American Psychological Association (APA)
Boguszewski, Andrzej& Teklinski, Andrew& Rosman, Howard& Desai, Devang& Ali, Sajid& Szpunar, Susan…[et al.]. 2012. The Sweet Spot : Continued Search for the Glycemic Threshold for Macrovascular Disease—A Retrospective Single Center Experience. ISRN Cardiology،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-505314
Modern Language Association (MLA)
Boguszewski, Andrzej…[et al.]. The Sweet Spot : Continued Search for the Glycemic Threshold for Macrovascular Disease—A Retrospective Single Center Experience. ISRN Cardiology No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-505314
American Medical Association (AMA)
Boguszewski, Andrzej& Teklinski, Andrew& Rosman, Howard& Desai, Devang& Ali, Sajid& Szpunar, Susan…[et al.]. The Sweet Spot : Continued Search for the Glycemic Threshold for Macrovascular Disease—A Retrospective Single Center Experience. ISRN Cardiology. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-505314
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-505314