Renal Dysfunction Is an Independent Risk Factor for Mortality after Liver Resection and the Main Determinant of Outcome in Posthepatectomy Liver Failure
Joint Authors
Stell, D. A.
Shahtahmassebi, G.
Bowles, M. J.
Aroori, S.
Wiggans, M. G.
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-05
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Introduction.
The aim of this study was to assess the interaction of liver and renal dysfunction as risk factors for mortality after liver resection.
Materials and Methods.
A retrospective analysis of 501 patients undergoing liver resection in a single unit was undertaken.
Posthepatectomy liver failure (PHLF) was defined according to the International Study Group of Liver Surgery (ISGLS) definition (assessed on day 5) and renal dysfunction according to RIFLE criteria.
90-day mortality was recorded.
Results.
Twenty-three patients died within 90 days of surgery (4.6%).
The lowest mortality occurred in patients without evidence of PHLF or renal dysfunction (2.7%).
The mortality rate in patients with isolated PHLF or renal dysfunction was 20% compared to 45% in patients with both.
Diabetes (P=0.028), renal dysfunction (P=0.030), and PHLF on day 5 (P=0.011) were independent predictors of 90-day mortality.
Discussion.
PHLF and postoperative renal dysfunction are independent predictors of 90-day mortality following liver resection but the predictive value for mortality is significantly higher when failure of both organ systems occurs simultaneously.
American Psychological Association (APA)
Wiggans, M. G.& Shahtahmassebi, G.& Bowles, M. J.& Aroori, S.& Stell, D. A.. 2013. Renal Dysfunction Is an Independent Risk Factor for Mortality after Liver Resection and the Main Determinant of Outcome in Posthepatectomy Liver Failure. HPB Surgery،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-505383
Modern Language Association (MLA)
Wiggans, M. G.…[et al.]. Renal Dysfunction Is an Independent Risk Factor for Mortality after Liver Resection and the Main Determinant of Outcome in Posthepatectomy Liver Failure. HPB Surgery No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-505383
American Medical Association (AMA)
Wiggans, M. G.& Shahtahmassebi, G.& Bowles, M. J.& Aroori, S.& Stell, D. A.. Renal Dysfunction Is an Independent Risk Factor for Mortality after Liver Resection and the Main Determinant of Outcome in Posthepatectomy Liver Failure. HPB Surgery. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-505383
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-505383