Postirradiation Osteosarcoma of the Maxilla : A Case Report and Current Review of Literature

Abstract EN

Background.

Radiation-induced sarcomas are well-known potential late sequelae of radiation therapy.

They are of rare occurrence in jaw bones and are even rarer in the maxilla.

Case report.

We report a case of radiation-induced osteosarcoma involving the maxilla in a patient treated with radiotherapy for nasopharyngeal carcinoma 14 years ago.

Despite neoadjuvant chemotherapy, surgical treatment could not be performed, and the patient received palliative chemotherapy.

Conclusions.

Radiation-induced osteosarcomas are aggressive and often elude early detection and timely intervention, rapidly leading to early demise of afflicted patients.

Long-term patient follow-up and a high index of suspicion are crucial for timely intervention.