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The Role of Granulysin in Cancer Immunology
Joint Authors
Morishita, Tetsuo
Okada, Satoshi
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-18
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Granulysin is a cytotoxic granule expressed in cytotoxic T cells and natural killer cells.
Although its cytotoxic effect against a number of tumor cell lines has been demonstrated in vitro, recent studies with transgenic mice, and a number of clinical studies, have further established its significance in cancer immunology.
Furthermore, granulysin-induced in vitro chemotaxis and activation of both human and mouse dendritic cells have been reported.
Given the results in recent clinical studies, granulysin may offer a useful indicator in the prognosis of cancer.
Taken together, an understanding of the mechanism by which granulysin destroys target cells would provide vital information in the development of new therapies for the treatment of this disease.
American Psychological Association (APA)
Okada, Satoshi& Morishita, Tetsuo. 2012. The Role of Granulysin in Cancer Immunology. ISRN Immunology،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-505468
Modern Language Association (MLA)
Okada, Satoshi& Morishita, Tetsuo. The Role of Granulysin in Cancer Immunology. ISRN Immunology No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-505468
American Medical Association (AMA)
Okada, Satoshi& Morishita, Tetsuo. The Role of Granulysin in Cancer Immunology. ISRN Immunology. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-505468
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-505468