From Genetics to Genomics of Epilepsy
Joint Authors
Cornacchione, Marisa
Di Costanzo, Alfonso
Garofalo, Silvio
Source
Neurology Research International
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-18, 18 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-08
Country of Publication
Egypt
No. of Pages
18
Main Subjects
Abstract EN
The introduction of DNA microarrays and DNA sequencing technologies in medical genetics and diagnostics has been a challenge that has significantly transformed medical practice and patient management.
Because of the great advancements in molecular genetics and the development of simple laboratory technology to identify the mutations in the causative genes, also the diagnostic approach to epilepsy has significantly changed.
However, the clinical use of molecular cytogenetics and high-throughput DNA sequencing technologies, which are able to test an entire genome for genetic variants that are associated with the disease, is preparing a further revolution in the near future.
Molecular Karyotype and Next-Generation Sequencing have the potential to identify causative genes or loci also in sporadic or non-familial epilepsy cases and may well represent the transition from a genetic to a genomic approach to epilepsy.
American Psychological Association (APA)
Garofalo, Silvio& Cornacchione, Marisa& Di Costanzo, Alfonso. 2012. From Genetics to Genomics of Epilepsy. Neurology Research International،Vol. 2012, no. 2012, pp.1-18.
https://search.emarefa.net/detail/BIM-505471
Modern Language Association (MLA)
Garofalo, Silvio…[et al.]. From Genetics to Genomics of Epilepsy. Neurology Research International No. 2012 (2012), pp.1-18.
https://search.emarefa.net/detail/BIM-505471
American Medical Association (AMA)
Garofalo, Silvio& Cornacchione, Marisa& Di Costanzo, Alfonso. From Genetics to Genomics of Epilepsy. Neurology Research International. 2012. Vol. 2012, no. 2012, pp.1-18.
https://search.emarefa.net/detail/BIM-505471
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-505471