The Effect of a Maternal Double Megadose of Vitamin A Supplement on Serum Levels of Retinol in Children Aged under Six Months
Joint Authors
Figueiroa, José Natal
Santos, Carmina Silva dos
Diniz, Alcides da Silva
Fernandes, Taciana
Andreto, Luciana Marques
de Arruda, Ilma Kruze Grande
Source
Journal of Nutrition and Metabolism
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-24
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objective.
To measure concentrations of serum retinol in children after the use of maternal vitamin A double megadose supplements.
Design.
Randomized controlled clinical trial.
Setting.
The study was conducted at two maternity hospitals in the city of Recife, in the northeast region of Brazil between August 2007 and June 2009.
Subjects and Methods.
276 children/mothers were recruited after birth and the women received a 200,000 IU capsule of vitamin A.
After ten days they were randomly assigned to two treatment groups.
One group received a second 200.000 IU capsule, while the other received a placebo.
The concentrations of retinol in the serum of the children from each group were measured at 2, 4, and 6 months.
Results.
173 children completed the study.
There was no difference between the two treatment groups (P=0.514).
The mean base retinol level was lower than that at four and six months (P<0.001).
Conclusions.
The maternal double megadose supplement had no additional effect on the serum retinol levels of the children, although concentrations of retinol in the children rose in the first six months of life.
This trial is registered with NCT00742937.
American Psychological Association (APA)
Santos, Carmina Silva dos& de Arruda, Ilma Kruze Grande& Fernandes, Taciana& Andreto, Luciana Marques& Figueiroa, José Natal& Diniz, Alcides da Silva. 2013. The Effect of a Maternal Double Megadose of Vitamin A Supplement on Serum Levels of Retinol in Children Aged under Six Months. Journal of Nutrition and Metabolism،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-505479
Modern Language Association (MLA)
Santos, Carmina Silva dos…[et al.]. The Effect of a Maternal Double Megadose of Vitamin A Supplement on Serum Levels of Retinol in Children Aged under Six Months. Journal of Nutrition and Metabolism No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-505479
American Medical Association (AMA)
Santos, Carmina Silva dos& de Arruda, Ilma Kruze Grande& Fernandes, Taciana& Andreto, Luciana Marques& Figueiroa, José Natal& Diniz, Alcides da Silva. The Effect of a Maternal Double Megadose of Vitamin A Supplement on Serum Levels of Retinol in Children Aged under Six Months. Journal of Nutrition and Metabolism. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-505479
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-505479