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The Role of Peroxisome Proliferator-Activated Receptors in Colorectal Cancer
Joint Authors
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-11
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Colorectal cancer is one of the most common cancers in the world.
Dietary fat intake is a major risk factor for colorectal cancer.
Some nuclear hormone receptors play an important role in regulating nutrient metabolism and energy homeostasis.
Among these receptors, special attention has been focused on the role of peroxisome proliferator-activated receptors (PPARs) in colorectal cancer, because PPARs are involved in regulation of lipid and carbohydrate metabolism.
PPARs are ligand-activated intracellular transcription factors.
The PPAR subfamily consists of three subtypes encoded by distinct genes named PPARα, PPARβ/δ, and PPARγ.
PPARγ is the most extensively studied subtype of PPARs.
Even though many investigators have studied the expression and clinical implications of PPARs in colorectal cancer, there are still many controversies about the role of PPARs in colorectal cancer.
In this paper, the recent progresses in understanding the role of PPARs in colorectal cancer are summarized.
American Psychological Association (APA)
Park, Joo-In& Kwak, Jong-Young. 2012. The Role of Peroxisome Proliferator-Activated Receptors in Colorectal Cancer. PPAR Research،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-505493
Modern Language Association (MLA)
Park, Joo-In& Kwak, Jong-Young. The Role of Peroxisome Proliferator-Activated Receptors in Colorectal Cancer. PPAR Research No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-505493
American Medical Association (AMA)
Park, Joo-In& Kwak, Jong-Young. The Role of Peroxisome Proliferator-Activated Receptors in Colorectal Cancer. PPAR Research. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-505493
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-505493