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Primary Nonfunction of Renal Allograft Secondary to Acute Oxalate Nephropathy
Joint Authors
Koffron, Alan
Zhang, Ping L.
Reddy, Gampala
Dumler, Francis
Pothugunta, Krishna
Parasuraman, Ravi
Samarapungavan, Dilip
Raofi, Vandad
Rocher, Leslie
Cohn, Steven
Source
Case Reports in Transplantation
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-28
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Primary nonfunction (PNF) accounts for 0.6 to 8% of renal allograft failure, and the focus on causes of PNF has changed from rejection to other causes.
Calcium oxalate (CaOx) deposition is common in early allograft biopsies, and it contributes in moderate intensity to higher incidence of acute tubular necrosis and poor graft survival.
A-49-year old male with ESRD secondary to polycystic kidney disease underwent extended criteria donor kidney transplantation.
Posttransplant, patient developed delayed graft function (DGF), and the biopsy showed moderately intense CaOx deposition that persisted on subsequent biopsies for 16 weeks, eventually resulting in PNF.
The serum oxalate level was 3 times more than normal at 85 μmol/L (normal <27 μmol/L).
Allograft nephrectomy showed massive aggregates of CaOx crystal deposition in renal collecting system.
In conclusion, acute oxalate nephropathy should be considered in the differential diagnosis of DGF since optimal management could change the outcome of the allograft.
American Psychological Association (APA)
Parasuraman, Ravi& Zhang, Ping L.& Samarapungavan, Dilip& Pothugunta, Krishna& Reddy, Gampala& Rocher, Leslie…[et al.]. 2011. Primary Nonfunction of Renal Allograft Secondary to Acute Oxalate Nephropathy. Case Reports in Transplantation،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-505527
Modern Language Association (MLA)
Parasuraman, Ravi…[et al.]. Primary Nonfunction of Renal Allograft Secondary to Acute Oxalate Nephropathy. Case Reports in Transplantation No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-505527
American Medical Association (AMA)
Parasuraman, Ravi& Zhang, Ping L.& Samarapungavan, Dilip& Pothugunta, Krishna& Reddy, Gampala& Rocher, Leslie…[et al.]. Primary Nonfunction of Renal Allograft Secondary to Acute Oxalate Nephropathy. Case Reports in Transplantation. 2011. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-505527
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-505527