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MicroRNAs : Promising New Antiangiogenic Targets in Cancer
Joint Authors
Calabuig-Fariñas, Silvia
Gallach, Sandra
Camps, Carlos
Jantus-Lewintre, Eloisa
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-14
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
MicroRNAs are one class of small, endogenous, non-coding RNAs that are approximately 22 nucleotides in length; they are very numerous, have been phylogenetically conserved, and involved in biological processes such as development, differentiation, cell proliferation, and apoptosis.
MicroRNAs contribute to modulating the expression levels of specific proteins based on sequence complementarity with their target mRNA molecules and so they play a key role in both health and disease.
Angiogenesis is the process of new blood vessel formation from preexisting ones, which is particularly relevant to cancer and its progression.
Over the last few years, microRNAs have emerged as critical regulators of signalling pathways in multiple cell types including endothelial and perivascular cells.
This review summarises the role of miRNAs in tumour angiogenesis and their potential implications as therapeutic targets in cancer.
American Psychological Association (APA)
Gallach, Sandra& Calabuig-Fariñas, Silvia& Jantus-Lewintre, Eloisa& Camps, Carlos. 2014. MicroRNAs : Promising New Antiangiogenic Targets in Cancer. BioMed Research International،Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-505573
Modern Language Association (MLA)
Gallach, Sandra…[et al.]. MicroRNAs : Promising New Antiangiogenic Targets in Cancer. BioMed Research International No. 2014 (2014), pp.1-14.
https://search.emarefa.net/detail/BIM-505573
American Medical Association (AMA)
Gallach, Sandra& Calabuig-Fariñas, Silvia& Jantus-Lewintre, Eloisa& Camps, Carlos. MicroRNAs : Promising New Antiangiogenic Targets in Cancer. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-14.
https://search.emarefa.net/detail/BIM-505573
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-505573