Is the Gut Microbiota a New Factor Contributing to Obesity and Its Metabolic Disorders?
Joint Authors
Major, Geneviève
Chou, Chieh J.
Harris, Kristina
Kassis, Amira
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-24
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
The gut microbiota refers to the trillions of microorganisms residing in the intestine and is integral in multiple physiological processes of the host.
Recent research has shown that gut bacteria play a role in metabolic disorders such as obesity, diabetes, and cardiovascular diseases.
The mechanisms by which the gut microbiota affects metabolic diseases are by two major routes: (1) the innate immune response to the structural components of bacteria (e.g., lipopolysaccharide) resulting in inflammation and (2) bacterial metabolites of dietary compounds (e.g., SCFA from fiber), which have biological activities that regulate host functions.
Gut microbiota has evolved with humans as a mutualistic partner, but dysbiosis in a form of altered gut metagenome and collected microbial activities, in combination with classic genetic and environmental factors, may promote the development of metabolic disorders.
This paper reviews the available literature about the gut microbiota and aforementioned metabolic disorders and reveals the gaps in knowledge for future study.Erratum of “Is the Gut Microbiota a New Factor Contributing to Obesity and Its Metabolic Disorders?”dx.doi.org/10.1155/2012/782920
American Psychological Association (APA)
Harris, Kristina& Kassis, Amira& Major, Geneviève& Chou, Chieh J.. 2012. Is the Gut Microbiota a New Factor Contributing to Obesity and Its Metabolic Disorders?. Journal of Obesity،Vol. 2012, no. 2012, pp.1-14.
https://search.emarefa.net/detail/BIM-505622
Modern Language Association (MLA)
Harris, Kristina…[et al.]. Is the Gut Microbiota a New Factor Contributing to Obesity and Its Metabolic Disorders?. Journal of Obesity No. 2012 (2012), pp.1-14.
https://search.emarefa.net/detail/BIM-505622
American Medical Association (AMA)
Harris, Kristina& Kassis, Amira& Major, Geneviève& Chou, Chieh J.. Is the Gut Microbiota a New Factor Contributing to Obesity and Its Metabolic Disorders?. Journal of Obesity. 2012. Vol. 2012, no. 2012, pp.1-14.
https://search.emarefa.net/detail/BIM-505622
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-505622