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Towards Improved Collagen Assessment : Polarization-Sensitive Optical Coherence Tomography with Tailored Reference Arm Polarization
Joint Authors
Brezinski, Mark E.
Vercollone, Christopher
Liu, Bin
Source
International Journal of Biomedical Imaging
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-14
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Single channel PS-OCT has advantages for assessing birefringent tissue components in various clinical scenarios, with implications for assessing pathology, ranging from osteoarthritis to myocardial infarction.
While the technique has been successfully used both in vitro and in vivo, there have been limited attempts to optimize single channel PS-OCT with respect to performance, particularly paddle rotation.
In this study, we developed and tested a new approach for the real-time assessment of birefringence through tailoring of reference arm polarization.
Different polarization rotation patterns, as depicted on a Poincare sphere, were assessed with polarization filters and retarders.
When further tested in tissue, PS-OCT assessments of bovine cartilage and tendon demonstrated that contrast was sensitive to the pattern selected, indicating that rotation pattern influenced birefringence assessment and providing insights into optimal patterns.
We also discuss the difference between diagnostic accuracy and precision with respect to both the construction and application of PS-OCT embodiments.
American Psychological Association (APA)
Liu, Bin& Vercollone, Christopher& Brezinski, Mark E.. 2012. Towards Improved Collagen Assessment : Polarization-Sensitive Optical Coherence Tomography with Tailored Reference Arm Polarization. International Journal of Biomedical Imaging،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-505946
Modern Language Association (MLA)
Liu, Bin…[et al.]. Towards Improved Collagen Assessment : Polarization-Sensitive Optical Coherence Tomography with Tailored Reference Arm Polarization. International Journal of Biomedical Imaging No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-505946
American Medical Association (AMA)
Liu, Bin& Vercollone, Christopher& Brezinski, Mark E.. Towards Improved Collagen Assessment : Polarization-Sensitive Optical Coherence Tomography with Tailored Reference Arm Polarization. International Journal of Biomedical Imaging. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-505946
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-505946