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Development of Vaccines against Visceral Leishmaniasis
Joint Authors
Kedzierski, Lukasz
Evans, Krystal J.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-05
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Leishmaniasis is a neglected disease resulting in a global morbidity of 2,090 thousand Disability-Adjusted Life Years and a mortality rate of approximately 60,000 per year.
Among the three clinical forms of leishmaniasis (cutaneous, mucosal, and visceral), visceral leishmaniasis (VL) accounts for the majority of mortality, as if left untreated VL is almost always fatal.
Caused by infection with Leishmania donovani or L.
infantum, VL represents a serious public health problem in endemic regions and is rapidly emerging as an opportunistic infection in HIV patients.
To date, no vaccine exists for VL or any other form of leishmaniasis.
In endemic areas, the majority of those infected do not develop clinical symptoms and past infection leads to robust immunity against reinfection.
Thus the development of vaccine for Leishmania is a realistic public health goal, and this paper summarizes advances in vaccination strategies against VL.
American Psychological Association (APA)
Evans, Krystal J.& Kedzierski, Lukasz. 2011. Development of Vaccines against Visceral Leishmaniasis. Journal of Tropical Medicine،Vol. 2012, no. 2012, pp.1-14.
https://search.emarefa.net/detail/BIM-505959
Modern Language Association (MLA)
Evans, Krystal J.& Kedzierski, Lukasz. Development of Vaccines against Visceral Leishmaniasis. Journal of Tropical Medicine No. 2012 (2012), pp.1-14.
https://search.emarefa.net/detail/BIM-505959
American Medical Association (AMA)
Evans, Krystal J.& Kedzierski, Lukasz. Development of Vaccines against Visceral Leishmaniasis. Journal of Tropical Medicine. 2011. Vol. 2012, no. 2012, pp.1-14.
https://search.emarefa.net/detail/BIM-505959
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-505959