Antimutagenic Effect of Medicinal Plants Achillea millefolium and Bauhinia forficata In Vivo
Joint Authors
Coelho, Ana Carolina
Düsman Tonin, Lilian Tatiani
Balbi, Thiago José
Vicentini, Veronica Elisa Pimenta
Almeida, Igor Vivian de
Düsman, Elisângela
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-12-29
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The investigation of traditionally used medicinal plants is valuable both as a source of potential chemotherapeutic drugs and as a measure of safety for the continued use of these medicinal plants.
Achillea millefolium L.
(AM) is an ancient remedial herb native to Europe that is used to treat wounds, gastrointestinal and hepatobiliary disorders, inflammation, headaches, and pain.
Bauhinia forficata Link (BF), an Asiatic plant, is one of the most commonly used plants in folk medicine against diabetes.
The aim of this study was to evaluate the cytotoxic and antimutagenic potential of aqueous extracts of AM and BF on bone marrow cells of Wistar rats treated in vivo.
These plant extracts possess considerable antioxidant activity due to the presence of flavonoids and phenolic compounds.
These compounds were determinants to noncytotoxic and antimutagenic/protective action of these plants, that reduced statistically the percentage of chromosomal alterations induced by the chemotherapeutic agent cyclophosphamide in simultaneous (AM, 68%; BF, 91%), pre- (AM, 68%; BF, 71%), and post-treatment (AM, 67%; BF, 95%).
Therefore, the results of this study indicate that extracts of A.
millefolium and B.
forficata have antimutagenic potential and that their consumption can benefit the health of those using them as an alternative therapy.
American Psychological Association (APA)
Düsman, Elisângela& Almeida, Igor Vivian de& Coelho, Ana Carolina& Balbi, Thiago José& Düsman Tonin, Lilian Tatiani& Vicentini, Veronica Elisa Pimenta. 2013. Antimutagenic Effect of Medicinal Plants Achillea millefolium and Bauhinia forficata In Vivo. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-505979
Modern Language Association (MLA)
Düsman, Elisângela…[et al.]. Antimutagenic Effect of Medicinal Plants Achillea millefolium and Bauhinia forficata In Vivo. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-505979
American Medical Association (AMA)
Düsman, Elisângela& Almeida, Igor Vivian de& Coelho, Ana Carolina& Balbi, Thiago José& Düsman Tonin, Lilian Tatiani& Vicentini, Veronica Elisa Pimenta. Antimutagenic Effect of Medicinal Plants Achillea millefolium and Bauhinia forficata In Vivo. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-505979
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-505979