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Modern Detection of Prostate Cancer's Bone Metastasis : Is the Bone Scan Era Over?
Joint Authors
Tombal, Bertrand
Lecouvet, Frederic
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-16
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Prostate cancer cells have an exquisite tropism for bone, which clinically translates into the highest rate of bone metastases amongst male cancers.
Although in the latest years there has been an active development of new “bone targeted” therapies, modern diagnostic techniques for bone metastases still relies mostly on 99mTc bone scanning (BS) and plain X-ray.
BS dramatically lacks specificity and sensitivity.
Recent publications using modern imaging technologies have clearly pinpointed that BS grossly underestimates the true prevalence of bone metastasis.
In addition BS does not allow tumour measurement and is, therefore, not appropriate to monitor response to therapy.
This might be extremely important in patients harbouring high-risk localized disease that are eventually candidate for local therapy.
Here we reviewed what are the emerging imaging strategies that are likely to supplant BS and to what extent they can be used in the clinic already.
American Psychological Association (APA)
Tombal, Bertrand& Lecouvet, Frederic. 2011. Modern Detection of Prostate Cancer's Bone Metastasis : Is the Bone Scan Era Over?. Advances in Urology،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-505998
Modern Language Association (MLA)
Tombal, Bertrand& Lecouvet, Frederic. Modern Detection of Prostate Cancer's Bone Metastasis : Is the Bone Scan Era Over?. Advances in Urology No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-505998
American Medical Association (AMA)
Tombal, Bertrand& Lecouvet, Frederic. Modern Detection of Prostate Cancer's Bone Metastasis : Is the Bone Scan Era Over?. Advances in Urology. 2011. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-505998
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-505998