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Two Cases of Small Cell Cancer of the Maxillary Sinus Treated with Cisplatin plus Irinotecan and Radiotherapy
Joint Authors
Nakamura, Kazuhiro
Sato, Hiroki
Tsukahara, Kiyoaki
Motohashi, Ray
Source
Case Reports in Otolaryngology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-01-29
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
Small cell carcinoma (SmCC) in the nasal cavity and paranasal sinuses is very rare, and definitive therapies have not yet been established.
Methods.
Chemoradiotherapy comprised 60 Gy of external radiation, with the administration of irinotecan intravenously at 60 mg/m2 on days 1, 8, and 15 and cisplatin at 60 mg/m2 on day 1.
Results.
Case 1 involved a 66-year-old woman with stage III cancer.
Adverse events included decreased white blood cells, anemia, and oral mucositis, all Grade 2.
The patient remained free of cancer as of 3 years and 6 months after completing the treatment.
Case 2 involved a 60-year-old man with stage IV cancer.
He also experienced adverse events of decreased white blood cells, anemia, and oral mucositis, all Grade 2.
He died after 11 months due to metastases throughout the body.
Conclusions.
The results suggest that this regimen may be tolerable as a therapy for this type of carcinoma.
American Psychological Association (APA)
Tsukahara, Kiyoaki& Nakamura, Kazuhiro& Motohashi, Ray& Sato, Hiroki. 2013. Two Cases of Small Cell Cancer of the Maxillary Sinus Treated with Cisplatin plus Irinotecan and Radiotherapy. Case Reports in Otolaryngology،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-506039
Modern Language Association (MLA)
Tsukahara, Kiyoaki…[et al.]. Two Cases of Small Cell Cancer of the Maxillary Sinus Treated with Cisplatin plus Irinotecan and Radiotherapy. Case Reports in Otolaryngology No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-506039
American Medical Association (AMA)
Tsukahara, Kiyoaki& Nakamura, Kazuhiro& Motohashi, Ray& Sato, Hiroki. Two Cases of Small Cell Cancer of the Maxillary Sinus Treated with Cisplatin plus Irinotecan and Radiotherapy. Case Reports in Otolaryngology. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-506039
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-506039