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In Vivo Assessment of Osseous Wound Healing Using a Novel Bone Putty Containing Lidocaine in the Surgical Management of Tooth Extractions
Joint Authors
Everett, Eric
Kumarswamy, Akshay
Moretti, Antonio
Paquette, David
Nares, Salvador
Padilla, Ricardo
Source
International Journal of Dentistry
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-13
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objective.
This preclinical pilot study evaluated the systemic, radiographic, and histological responses to bone putty containing lidocaine in a canine tooth extraction model.
Methods.
In five beagle dogs the right mandibular premolars were extracted and sockets grafted with (1) xenograft particulate bone and a collagen sponge plug (control), (2) bone putty alone, (3) bone putty mixed with xenograft (3 : 1), or (4) xenograft sandwiched between bone putty.
At 6 weeks post-op, the systemic and local responses were evaluated using a blood chemistry panel, micro-CT, and histological analyses.
Results.
No significant differences in blood chemistries were noted at 6 weeks postgrafting compared to baseline.
Sockets grafted with either bone putty formulation demonstrated comparable radiographic and histologic evidence of bone healing compared to control sockets.
Conclusions.
Our preclinical results indicate that this bone putty appears to be a safe biocompatible device that may be useful in the postoperative management of tooth extractions.
American Psychological Association (APA)
Kumarswamy, Akshay& Moretti, Antonio& Paquette, David& Padilla, Ricardo& Everett, Eric& Nares, Salvador. 2012. In Vivo Assessment of Osseous Wound Healing Using a Novel Bone Putty Containing Lidocaine in the Surgical Management of Tooth Extractions. International Journal of Dentistry،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-506131
Modern Language Association (MLA)
Kumarswamy, Akshay…[et al.]. In Vivo Assessment of Osseous Wound Healing Using a Novel Bone Putty Containing Lidocaine in the Surgical Management of Tooth Extractions. International Journal of Dentistry No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-506131
American Medical Association (AMA)
Kumarswamy, Akshay& Moretti, Antonio& Paquette, David& Padilla, Ricardo& Everett, Eric& Nares, Salvador. In Vivo Assessment of Osseous Wound Healing Using a Novel Bone Putty Containing Lidocaine in the Surgical Management of Tooth Extractions. International Journal of Dentistry. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-506131
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-506131