Experimental Evaluation of the Pathogenicity of Different Strains of Schistosoma mansoni
Joint Authors
Zanotti-Magalhães, Eliana Maria
Zuim, Nádia Regina Borim
Magalhães, Luiz Augusto
Euzébio, Antônio Aurélio
Linhares, Arício Xavier
Source
Interdisciplinary Perspectives on Infectious Diseases
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-07
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The pathogenesis of three different Schistosoma mansoni strains from the Brazilian states of Minas Gerais (BH strain) and São Paulo (SJ and SD strains) was evaluated in experimentally infected mice.
Observations of the most severe clinical cases among local patients treated (SD strain) in the city of Campinas (São Paulo, Brazil) formed the basis of this study.
Mice were used as definitive hosts and were infected with cercariae from Biomphalaria tenagophila (SJ and SD strains) and Biomphalaria glabrata (BH strains).
The parameters analyzed were as follows: number of S.
mansoni eggs in mice feces; number of granulomas per tissue area in liver, spleen, lungs, pancreas, and ascending colon; measurements of hepatic and intestinal granulomas; number of adult worms; and measurements of trematode eggs.
The comparison among the three strains indicated that the SD strain, isolated in Campinas, presented a higher worm recovery relative to the number of penetrating cercariae.
In addition, when compared to the SJ and BH strains, the SD strain demonstrated similar pathogenicity to the BH strain, with a greater quantity of granulomas in the viscera, as well as larger granulomas and eggs.
Furthermore, a greater quantity of trematode eggs was also shed in the feces.
American Psychological Association (APA)
Euzébio, Antônio Aurélio& Zuim, Nádia Regina Borim& Linhares, Arício Xavier& Magalhães, Luiz Augusto& Zanotti-Magalhães, Eliana Maria. 2012. Experimental Evaluation of the Pathogenicity of Different Strains of Schistosoma mansoni. Interdisciplinary Perspectives on Infectious Diseases،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-506150
Modern Language Association (MLA)
Euzébio, Antônio Aurélio…[et al.]. Experimental Evaluation of the Pathogenicity of Different Strains of Schistosoma mansoni. Interdisciplinary Perspectives on Infectious Diseases No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-506150
American Medical Association (AMA)
Euzébio, Antônio Aurélio& Zuim, Nádia Regina Borim& Linhares, Arício Xavier& Magalhães, Luiz Augusto& Zanotti-Magalhães, Eliana Maria. Experimental Evaluation of the Pathogenicity of Different Strains of Schistosoma mansoni. Interdisciplinary Perspectives on Infectious Diseases. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-506150
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-506150