Experimental Evaluation of the Pathogenicity of Different Strains of Schistosoma mansoni

Joint Authors

Zanotti-Magalhães, Eliana Maria
Zuim, Nádia Regina Borim
Magalhães, Luiz Augusto
Euzébio, Antônio Aurélio
Linhares, Arício Xavier

Source

Interdisciplinary Perspectives on Infectious Diseases

Issue

Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2012-11-07

Country of Publication

Egypt

No. of Pages

7

Main Subjects

Diseases
Medicine

Abstract EN

The pathogenesis of three different Schistosoma mansoni strains from the Brazilian states of Minas Gerais (BH strain) and São Paulo (SJ and SD strains) was evaluated in experimentally infected mice.

Observations of the most severe clinical cases among local patients treated (SD strain) in the city of Campinas (São Paulo, Brazil) formed the basis of this study.

Mice were used as definitive hosts and were infected with cercariae from Biomphalaria tenagophila (SJ and SD strains) and Biomphalaria glabrata (BH strains).

The parameters analyzed were as follows: number of S.

mansoni eggs in mice feces; number of granulomas per tissue area in liver, spleen, lungs, pancreas, and ascending colon; measurements of hepatic and intestinal granulomas; number of adult worms; and measurements of trematode eggs.

The comparison among the three strains indicated that the SD strain, isolated in Campinas, presented a higher worm recovery relative to the number of penetrating cercariae.

In addition, when compared to the SJ and BH strains, the SD strain demonstrated similar pathogenicity to the BH strain, with a greater quantity of granulomas in the viscera, as well as larger granulomas and eggs.

Furthermore, a greater quantity of trematode eggs was also shed in the feces.

American Psychological Association (APA)

Euzébio, Antônio Aurélio& Zuim, Nádia Regina Borim& Linhares, Arício Xavier& Magalhães, Luiz Augusto& Zanotti-Magalhães, Eliana Maria. 2012. Experimental Evaluation of the Pathogenicity of Different Strains of Schistosoma mansoni. Interdisciplinary Perspectives on Infectious Diseases،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-506150

Modern Language Association (MLA)

Euzébio, Antônio Aurélio…[et al.]. Experimental Evaluation of the Pathogenicity of Different Strains of Schistosoma mansoni. Interdisciplinary Perspectives on Infectious Diseases No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-506150

American Medical Association (AMA)

Euzébio, Antônio Aurélio& Zuim, Nádia Regina Borim& Linhares, Arício Xavier& Magalhães, Luiz Augusto& Zanotti-Magalhães, Eliana Maria. Experimental Evaluation of the Pathogenicity of Different Strains of Schistosoma mansoni. Interdisciplinary Perspectives on Infectious Diseases. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-506150

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-506150